The lack of appropriate animal models has hampered efforts to develop therapies for Duchenne muscular dystrophy (DMD). A new mouse model lacking both dystrophin and telomerase (Sacco et al., 2010) closely mimics the pathological progression of human DMD and shows that muscle stem cell activity is a key determinant of disease severity.

From the Department ofPathologe and Institute ofInfectious Diseases,t University ofMilano, "L. SACCO" Hospital, Milan, Italy; Department ofPathologj and Institute ofHematology,§ University ofPavia, Policlinico San Matteo-IRCCS, Instituto Ricovero & Cura Carattere Scientifico, Research Unit, Pavia, Italy; Department ofPathology,7 Columbia University College of Physicians and Surgeons, New York, ...

Department of Dermatology, University of Pennsylvania, Philadelphia, USA; Rheumatology Unit, L Sacco Hospital University of Milan, Milan, Italy; Rheumatology Unit, Department of Internal Medicine, University of Pisa, Pisa, Italy; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, USA; Departments of Dermatology, Pathology and Internal Medicine, Cer...

This research aims to understand the different success factors of a savings and credit cooperative (SACCO) through study managerial dimensions its style governance. Semi-directed interviews were conducted with three directors who are founding members Haitian ‘MEN ALE MEN VINI (MAMEV)’ cooperative. NVIVO version 11 software was used as tool for coding data analysis. The concluded that is linked ...

Shi-Lin Zhu, C. M. Maekawa, G. Sacco, B. R. Holstein, and M. J. Ramsey-Musolf Department of Physics, University of Connecticut, Storrs, Connecticut 06269 Kellogg Radiation Laboratory, California Institute of Technology, Pasadena, California 91125 Department of Physics, University of Massachusetts, Amherst, Massachusetts 01003 Theory Group, Thomas Jefferson National Accelerator Facility, Newport...

To cite this article: Joseph J. Sacco, Mererid Evans, Kevin J Harrington, Stephen Man, Ned Powell, Richard J Shaw & Terry M. Jones (2015): Systemic listeriosis following vaccination with the attenuated Listeria monocytogenes therapeutic vaccine, ADXS11-001, Human Vaccines & Immunotherapeutics, DOI: 10.1080/21645515.2015.1121338 To link to this article: http://dx.doi.org/10.1080/21645515.2015.11...

I read with interest the article by Sacco et al entitlted “TakoTsubo like Syndrome Triggered by Meperidine” on anaphylaxis probably causing takotsubo syndrome . Takotsubo cardiomyopathy is also called stress induced cardiomyopathy or the broken heart syndrome. It is most commonly triggered by emotional stress causing transient apical and/or apical left ventricular systolic dysfunction in the ab...

Coronary artery bypass grafting: on-pump or off-pump? With a growing evidence base surrounding off-pump cardiac surgery, Confluence spoke to Professor Massimo G Lemma, Luigi Sacco University General Hospital, Milan, Italy about how the results of his most recent study investigating on-pump versus off-pump coronary artery bypass surgery in high-risk patients might impact clinical practice. m g L...

We have studied the contribution of ciliate protozoa to the degradation of dietary protein, utilizing 5 defaunated and 6 faunated sheep. Rumen samples from these animals were used as inocular for in vitro determination of the degradability of different protein sources: lupine grain, peanut and soybean cake, and fish meal. We also applied the in sacco method to measure the digestibility of soybe...