نتایج جستجو برای: immunotoxicity
تعداد نتایج: 652 فیلتر نتایج به سال:
New approaches to immunotoxicity testing are reviewed and discussed. A method of activating T-cells in vivo is presented which circumvents artifacts dur to viability effects encountered with in vitro mitogen assays. The use of adoptive transfer approaches to combine the advantages of in vitro manipulation with in vivo function assays is discussed relative to natural killer cells. The need for a...
Several organophosphate and organochlorine compounds, including pesticides commonly found in the Great Lakes basin, have the potential to induce immunotoxicity. Because of biomagnification and accumulation in the food chain, Great Lakes residents may inadvertently be exposed to these compounds and thus face increased risk of immune dysfunction. In spite of the laboratory animal data and evidenc...
*Institut National de la Recherche Scientifique-Institut Armand-Frappier (INRS-IAF), Pointe-Claire, QC H9R 1G6, Canada †Departement of Fisheries and Oceans, Institut Maurice-Lamontagne, Mont-Joli, QC G5H 3Z4, Canada ‡Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK S7N 5B4, Canada §Biomedical Sciences, Ontario Veterinary College Medicine, Guelph, ON N1G 2W1, Can...
Role of metabolism by intestinal bacteria in arbutin-induced immunotoxicity was investigated in splenocyte cultures. Following an incubation of arbutin with 5 different intestinal bacteria for 24 hr, its aglycone hydroquinone could be produced and detected in the bacterial culture media with different amounts. Toxic effects of activated arbutin by intestinal bacteria on lymphoproliferative resp...
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