SUMMARY Refractory celiac disease is an uncommon condition which might be associated to poor prognosis. It often treated with immunosuppressive medications, results. divided in type 1 and 2, the latter carrying a high risk for lymphoma mortality. A case of 41 year old female patient refractory 2 reported. She was oral budesonide six months, achieving histological remission.

Crohn's disease (CD) is characterized by transmural inflammation of the gastrointestinal tract leading to inflammatory, stricturing and/or and fistulizing disease. Once a patient develops medically refractory disease, mechanical obstruction, fistulizing disease or perforation, surgery is indicated. Unfortunately, surgery is not curative in most cases, underscoring the importance of bowel preser...

In the context of prospective trials of immunosuppressive drugs in systemic lupus erythematosus (SLE) nephritis, 83 patients were studied with regard to development of herpes zoster. Herpes zoster was found to occur with high frequency (21%) in patients with SLE nephritis treated with immunosuppressive agents. The course of herpes zoster was benign: no deaths occurred and only 2 of the 18 patie...

Post renal transplantation, therapeutic drug monitoring of immunosuppressive medications, particularly calcineurin inhibitors, is vital to ensure adequate immunosuppression, prevent nephrotoxicity and neurotoxicity, undue risk opportunistic infections. Tacrolimus has emerged as the preferred CNI over years due its association with reduced rates rejection. An important consideration among patien...

conclusions this rare observation supports the role of immunosuppressive therapy in preventing the recurrence of life-threatening vascular lesions in the management of behcet’s disease. introduction arterial involvement in behcet’s disease has been previously described. we report a rare case of a large and long-segment thoracoabdominal aneurysm, which was associated with behcet’s disease and ha...