BACKGROUND Mycophenolate mofetil (MMF) is an immunosuppressive drug widely used in solid organ transplantation, and it may play an increasing role in autoimmune disease. MMF has been introduced as a novel immunosuppressive agent in systemic lupus erythematosus (SLE), often in patients intolerant of or resistant to conventional immunosuppressive regimens. METHODS We studied 21 patients with SL...

Post transplant patients are more vulnerable to the opportunistic fungal infections secondary long -standing treatment on immunosuppressive therapy. A conscientious look in post renal transplant patients view of any is crucial. Aureobasidium pullulans an agent responsible for various pathologies leading nodules with ulceration on skin and systemic infection abcess formation viscera. Keyw...

The immunosuppressive agent FK permitted increased kidney transplant survival in dogs over a wide dose range, but with weight loss and manifold evidence of toxicity. The best use of FK at low doses was in combination with CyA and Pred.

A whole variety of chemical and biological materials have immunosuppressive effects in animals. Although anti-inflammatory agents, especially the corticosteroids, are inhibitors of the immune response, most are general cytotoxic agents. The cytotoxic agents were first developed as antitumour agents. It is now well known that they are not particularly selective for cancer cells, but are selectiv...

the immunosuppressive effect of antimacrophage serum (ams) on the primary immune response of mice to sheep red blood cells (srbc) was studied. ams, given before a small dose of antigen, abrogated the immune response. transplantation of normal, galss-adherent macrophages enabled ams-treated animals to respond to srbc, while administration of lymph node lymphocytes did not reveres ams - induced i...

the adsorptive behavior of the immunosuppressive agent tacrolimus was studied by cyclic and differential-pulse voltammetry on a hanging mercury drop electrode (hmde). the drug was accumulated at hmde and two well-defined peak currents were obtained at -1353 and -1417 mv vs . sce (saturated kcl) in borate buffer (ph 10.0) + 0.1 kcl solution. a voltammetric procedure was developed for the determi...

PURPOSE Co-occurrence of Guillain-Barré syndrome (GBS) and other autoimmune diseases is rare. We present the case of a patient with co-occurrence of GBS and primary Sjögren syndrome (pSS). CASE REPORT An 82-year-old woman presented with acute ascending flaccid paralysis and acute respiratory failure. Nerve conduction studies and cerebrospinal fluid analysis confirmed the diagnosis of GBS of a...