the diagnosis of celiac disease (cd) relies on the concordance of pathological, serological, genetic and clinical features. for this reason, the diagnosis of cd is often a challenge. seronegative celiac disease (sncd) is defined by the negativity of anti-tissue transglutaminase antibodies in the presence of a positive histology on duodenal biopsy samples, i. e. inflammatory infiltrate of intra-...

background: the infection in the neonatal period is a significant cause of mortality in the preterm neonates. the transfer of the immunoglobulin from mother to fetus occurs mainly after 32 to 34 weeks of gestation. therefore, preterm neonates are relatively immune compromised. the aim of the study was to evaluate the impact of intravenous immunoglobulin on mortality rates reduction in preterm n...

As IgM and IgA-enriched preparations are needed to complete the immunotherapeutic spectrum, a simple procedure is described for the preparation of IgM and IgA enriched immunoglobulins. Fraction III which was prepared by cold ethanol fractionation was treated by octanoic acid followed by ethanol precipitation and ion-exchange chromatography using Sephadex DEAE A-50 and 0.1 M tris-D.35M NaCI ...

autoimmune pancreatitis is a fibro-inflammatory form of chronic pancreatitis. it is diagnosed by the combination of imaging studies such as a ct scan and pancreatography, laboratory analyses that include igg4 and/or autoantibodies, histopathological evaluations and positive response to corticosteroid therapy. we report the case of a 41-year-old female with a history of jaundice and increasing a...

introduction: knowledge of emergency medicine residents about the management of patients suspected of having tetanus favoring wounds is very important due to their responsibility for the treatment of such patients. the aim of the present study was to evaluate this knowledge and making sure of the adequacy of instructions they have received in relation to prevention of tetanus.  methods: a relia...

previous, intravenous immunoglobulin (ivig) has been used for treatment of patients with immunodeficiency. however, recent studies have shown that ivig is a suitable approach for treatment of inflammatory and autoimmune diseases. although the exact mechanism of ivig action is not well known, recent findings have demonstrated that ivig impacts on expression and function of fc receptors of immuno...

background: infertility is one of the common problems seen in couples of reproductive age. presence of antisperm antibodies in semen and serum are amongst the causes of immunoinfertility. this study was performed to determine antisperm antibodies in cervicovaginal secretions and serum of infertile women and also measure serum levels of immunoglobulins (igg, igm and iga). methods: the study cons...

background: determination of reference ranges of each serum protein in normal population of each country is required for studies and clinical interpretation. the aim of this study was defining reference range values of immunoglobulins and complement components in iranian healthy children. methods: this study was conducted from june 2003 to june 2006 in immunology, asthma and allergy research in...

Immunoglobulin, which is also called an antibody, a type of serum protein produced by B cells that can specifically bind to the corresponding antigen. Immunoglobulin closely related many diseases and plays key role in medical biological circles. Therefore, use effective methods improve accuracy immunoglobulin classification great significance for disease research. In this paper, CC–PSSM monoTri...

previous, intravenous immunoglobulin (ivig) has been used for treatment of patients with immunodeficiency. however, recent studies have shown that ivig is a suitable approach for treatment of inflammatory and autoimmune diseases. although the exact mechanism of ivig action is not well known, recent findings have demonstrated that ivig impacts on expression and function of fc receptors of immuno...