As increased numbers of immunocompromised persons present to the emergency department (ED), it is essential that emergency physicians possess the knowledge and skills to recognize and to treat infectious complications of cancer, organ transplantation, diabetes, renal failure, cirrhosis, asplenism, human immuno­ deficiency virus (HIV) infection, and other immunosuppressive conditions. These incl...

SUMMARY The number of patients with acquired immunodeficiency has grown steadily as a result of both a larger number of patients receiving solid organ and hematopoietic stem cell transplants and their longer survival times. The use of newer, more potent immunosuppressive regimens has increased the frequency of severe adenovirus infections. Human adenoviruses are a large group of viruses, repres...

Over the past 20–30 years there has been a dramatic increase in the number of people living with immunosuppression. Cancer chemotherapy and the treatment of haematological disease transiently put people at risk, while the immunosuppression required for solid organ transplants and for immunemediated diseases, such as systemic lupus erythematosus, is more prolonged. In addition to these iatrogeni...