Catalytic oxidation of amine to imine is of intense present interest since imines are important intermediates for the synthesis of fine chemicals, pharmaceuticals, and agricultural chemicals. However, considerable efforts have been made to develop efficient methods for the oxidation of secondary amines to imines, while little attention has until recently been given to the oxidation of primary a...

Nanodroplets of sulfur-stabilised copper nanoparticles effectively catalyse the aerobic oxidation amines to imines under ambient conditions.

Interactions of 2-, 3- and 4-formyl phenylboronic acids (FPBAs) with sugars, amino sugars, aminoglycosides and various poly- and monoamines have been studied by UV-vis, (1)H and (11)B NMR titrations in water at variable pH. Behavior of 2-FPBA was anomalous in several aspects. Transformation of the acid into its conjugate base was slow in NMR time scale and was accompanied by intramolecular cycl...

Two new fates of imine intermediates formed on radical cyclizations of ene-sulfonamides have been identified, reduction and hydration/fragmentation. Tin hydride-mediated cyclizations of 2-halo-N-(3-methyl-N-sulfonylindole)anilines provide spiro[indoline-3,3'-indolones] or spiro-3,3'-biindolines (derived from imine reduction), depending on the indole C2 substituent. Cyclizations of 2-haloanilide...

Silyl ketene imines derived from a variety of alpha-branched nitriles have been developed as highly useful reagents for the construction of quaternary stereogenic centers via the aldol addition reaction. In the presence of SiCl4 and the catalytic action of chiral phosphoramide (R,R)-5, silyl ketene imines undergo extremely rapid and high yielding addition to a wide variety of aromatic aldehydes...

Miscellaneous imines and acyl hydrazones were prepared from 5-nitrofuraldehyde 5-nitrothiophene-2-carboxaldehyde. Their activities against Toxoplasma gondii Leishmania major parasites evaluated. Promising antiparasitic effects selectivities observed for certain imines. Cobalt(II) copper(II) complexes conserved the high anti-Toxoplasma of 3-hydroxy-2-naphthoic carboxyl hydrazone (2a). In additio...

Low-valency titanium species, generated in situ by using Ti(OiPr)4/2 c-C5H9MgCl reagent, react with imines to give a titanium-imine complex that can couple with terminal alkynes to provide azatitanacyclopentenes with excellent regioselectivity. Stereodefined allylic amines are obtained in good yields after hydrolysis or iodonolysis of the corresponding azatitanacyclopentenes. When ethynylcyclop...