نتایج جستجو برای: imidazolone

تعداد نتایج: 93  

Journal: :European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies 1997
G Münch R Keis A Wessels P Riederer U Bahner A Heidland T Niwa H D Lemke R Schinzel

Recent studies suggest that advanced glycation endproducts play an important role in cardiovascular complications of ageing, diabetes and end-stage renal failure. Since highly elevated levels of advanced glycation endproducts are present in serum of patients on maintenance haemodialysis, an accurate and rapid assay for their determination would be useful. This would be particularly valuable for...

2014
Nishanka Dilini Ratnayake Nan Liu Leslie A. Kuhn Kevin D. Walker

7 ABSTRACT: β-Amino acids are emerging as an important class of 8 compounds in medicinal chemistry. β-Aryl-β-alanines show antiepilepto9 genesis activity, while others have been used to synthesize antibiotic β10 peptides. To assess the utility of a methylidene imidazolone-dependent 11 Pantoea agglomerans phenylalanine aminomutase (PaPAM) for making 12 non-natural β-amino acids, we surveyed the ...

Journal: :Biochemistry 2010
Benjamin D Krentz Heidi J Mulheron Jeremy D Semrau Alan A Dispirito Nathan L Bandow Daniel H Haft Stéphane Vuilleumier J Colin Murrell Marcus T McEllistrem Scott C Hartsel Warren H Gallagher

Methanobactins (mb) are low-molecular mass, copper-binding molecules secreted by most methanotrophic bacteria. These molecules have been identified for a number of methanotrophs, but only the one produced by Methylosinus trichosporium OB3b (mb-OB3b) has to date been chemically characterized. Here we report the chemical characterization and copper binding properties of a second methanobactin, wh...

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