نتایج جستجو برای: il17
تعداد نتایج: 451 فیلتر نتایج به سال:
Th17 and regulatory T (Treg) cells are integral in maintaining immune homeostasis and Th17-Treg misbalance associates with inflammation. We demonstrate that in addition to natural (n)Treg and induced (i)Treg cells developed from naïve precursors, Th17 cells are a novel source of Foxp3 cells by converting into ex-Th17 Foxp3 cells, and this helps to reconcile the contradictory information about t...
BACKGROUND Haemodynamic impairment, inflammatory mediators and glucose metabolism disturbances have been implicated in the pathogenesis of Non-Alcoholic Fatty Liver Disease (NAFLD). AIM To investigate the cytokine profile in NAFLD patients in peripheral (P) and hepatic venous (HV) blood and to compare with histology, haemodynamic and metabolic parameters. METHODS 40 obese patients with an i...
Background IL17 is a cytokine produced by activated helper lymphocytes Th17. It plays a role in the mechanisms of allergic reactions involving neutrophils through the induction of poduction cytokines and chemokines. Affects the activation, recruitment and migration of neutrophils into the tissue by regulating inflammatory reaction. Activated neutrophils secrete elastase and ROS (reactive oxygen...
Background Th17 cells are a recently characterised, highly proinflammatory subset of T cells. We have shown that Th17 numbers are elevated in JIA synovial fluid and are significantly higher in extended than persistent oligoarthritis patients [1]. Interestingly we noted a high number of synovial T cells which produce both IL17 and interferon gamma (IFNγ). We also demonstrated that Th17 are activ...
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