oral allergy syndrome (oas) is occasionally observed following consumption  of raw fruits  in  allergic adults. since this  phenomenon  was  commonly  reported  in  khorasan province of iran; we intended to check if common  diagnostic tests could be applied for differential diagnosis of oas to grapes. ige reactivity of 84 patients with oas to grape and 34 patients with oas to other fruits were ...

he commonest epileptic syndrome is the so-called idiopathic generalised epilepsy (IGE), which accounts for at least a third of all cases of epilepsy in the community. 1 This proportion is even higher in the paediatric age range. The syndrome is characterised by the presence of generalised tonic clonic, myo-clonic, and typical absence seizures on their own or in different combinations. The onset...

syndrome (CLICKMAS el al . , 1985). Small amounts of antigen, presumably circulating in these conditions, can stimulate the production ‘of specific IgE rather than IgG. Our results would seem to support this hypothesis: the greater sensitivity of the IgE test makes it possible to recognize clinical cases of OLM which are missed with IgG ELISA. In a comprchensive laboratory diagnosis, both IgG a...

Th e hyper-IgE recurrent infection syndromes (HIES) comprise a group of primary immunodefi ciency dis orders that exhibit markedly elevated IgE levels, recur rent staphylococcal skin abscesses, eczema and pulmonary infections. Both autosomal dominant and autosomal recessive forms of the disorder have been described. Most autosomal dominant HIES (AD-HIES) have been found to be due to mutations i...

Understanding how class switch recombination (CSR) is regulated to produce immunoglobulin E (IgE) has become fundamental because of the dramatic increase in the prevalence of IgE-mediated hypersensitivity reactions. CSR requires the induction of the enzyme AICDA in B cells. Mutations in AICDA have been linked to Hyper-IgM syndrome (HIGM2), which shows absence of switching to IgE as well as to I...

Objective. To study predictors of bronchial asthma development in children 3-4 years old with recurrent broncho-obstructive syndrome by 5-6 age. Material and methods. The authors conducted a prospective cohort 2018-2020 the participation 61 aged 3–4 syndrome. Inclusion criteria: age years; ? 3 episodes past 12 months; informed voluntary consent. At first visit scientists determined levels serum...

Background The measurement of total serum IgE is made in some cases to investigate if there is the occurrence of allergic processes. However, does not identify specific antibodies. When it is high may indicate an allergic process, or the ability to initiate some. However, increased IgE levels may also indicate other problems such as parasitic diseases, IgE myeloma, hyper-IgE syndrome and some s...

A dog with Japanese cedar (Cryptomeria japonica, CJ) pollinosis had oral allergy syndrome (OAS) after ingesting fresh tomato. The dog showed specific IgE to both CJ and tomato allergens. As a negative control, twenty dogs without atopic dermatitis that had no exposure to tomato and no specific IgE to CJ allergen were used. They had no specific IgE to tomato allergen. Furthermore, IgE cross-reac...

The novel cytokine IL-31 and its receptor have been shown to play a central role in bridging the immune system with neurons, epithelial surfaces connective tissues. Although increasing evidence has demonstrated their inflammation, involvement expansion of distinct leukocyte subsets is not fully understood. Detailed analyses Il31-transgenic (Eμ-Lck) mice indicated that next induction pruritus sk...