OBJECTIVES To analyse the prevalence and complications of uveitis and their predictors in a large cohort of patients with juvenile idiopathic arthritis (JIA). METHODS Data of 3271 JIA patients as classified by International League of Associations for Rheumatology (ILAR) criteria included in a national database during 1 yr were analysed. RESULTS Uveitis prevalence was 12% of all JIA patients...

BACKGROUND Juvenile idiopathic arthritis is the most common rheumatic disease in children. Chronic uveitis is a common and serious comorbid condition of juvenile idiopathic arthritis, with insidious presentation and potential to cause blindness. Knowledge of clinical associations will improve risk stratification. Based on clinical observation, we hypothesized that allergic conditions are associ...

purpose : to review epidemiological aspects of uveitis in asia and compare it with few major reports from outside of this continent methods : we have reviewed 522 articles concerning the causes and patterns of uveitis and 22 major epidemiology reviews, registered from 1962 to 2009 in medline-database. we have selected 7 major reviews from asia and compared it with five major articles from afric...

AIM To find a laboratory indicator for systemic involvement in intermediate uveitis. METHODS Interleukin 8 (IL-8) and C reactive protein (CRP) serum levels were measured in patients with idiopathic intermediate uveitis (n = 61), uveitis controls (n = 143), and normal controls (n = 29). The records of those with intermediate uveitis were reviewed with the emphasis on disease activity and sever...

Uveitis is a clinical feature of the Blau syndrome, a disease linked to CARD15 (also referred to as NOD2) mutations. Three main mutations in this gene (R334W, R334Q and L469F) have been reported as Blau syndrome risk factors, a disease that manifests uveitis as one of its clinical features. However, little is known on the involvement of this gene in idiopathic uveitis. We thus sought to determi...

Uveitis is estimated to account for 10% of blindness in people of working age in the Western world. A retrospective review of patients attending a uveitis clinic in the United Kingdom found that 70% of patients had visual impairment (visual acuity 6/18 or worse) and half of these patients had bilateral visual impairment. Acute anterior uveitis, which is the most common form of uveitis in the UK...

Granuloma annulare is self-limiting cutaneous condition of unknown etiology, causing necrobiotic dermal and subcutaneous papules. A number of conditions have been described in association with Granuloma annulare, including lymphoma, anemia, intestinal bleeding, seronegative arthralgia, vasculitis and autoimmune thyroiditis. This manuscript, as the first report of this combination in Iran, descr...

Background: Uveitis is the inflammation of uveal components eye (iris, choroid and retina) third leading cause blindness in world. It less common children than adults. Young are usually diagnosed late, as they cannot express their complaints. Objectives: With this work; We aimed to contribute literature by determining underlying primary diagnosis evaluating treatment response patients who were ...

BACKGROUND/AIMS The clinical course for childhood chronic anterior uveitis can vary from mild, self limiting disease to bilateral blindness. The purpose of this study was to identify those risk factors at onset that predict disease severity. METHODS A retrospective case note review of all patients with painless anterior uveitis diagnosed from 1982 to 1998. Patients were divided into two cohor...

Bilateral chronic anterior uveitis is an extra-articular feature of juvenile idiopathic arthritis. Although figures vary, uveitis occurs in approximately 11%-13% of patients with this disease and is most commonly associated with the female gender, oligoarthritis, and presence of antinuclear antibodies. The disease has an insidious onset and is often asymptomatic. Managing patients with juvenile...