Owing to the overlapping absorption bands of hemoglobin and bilirubin, spectrophotometric determination of plasma free hemoglobin has been plagued by the interference of bilirubin when the latter is present in significant concentrations. To resolve this problem, bilirubin oxidase from Myrothecium verrucaria has been used to remove bilirubin in icteric samples. The enzyme converts bilirubin to b...

Background Leptospirosis is a zoonosis caused by the infection of pathogenic bacteria of the genera Leptospira, often transmitted by direct or indirect contact with urine of infected animal hosts [1]. In national territory, leptospirosis is considered an endemic disease, with high incidence in raining seasons, but occurring during the whole year [2]. From all the cases, 15% evolve to the icteri...

We describe the first case of cefotetan-induced immune hemolytic anemia (IHA) following sacrocolpopexy. A 65-year-old female status post uncomplicated sacrocolpopexy presented on postoperative day 15 for worsening fatigue. Her exam was notable jaundice and icteric sclerae. Hemoglobin hematocrit were 5.5 g/dL 17.2%, respectively direct anti-globin test positive.

Materials and Methods: This two-year retrospective study of 1800 jaundiced term-neonates studied 355 cases due to ABO incompatibility divided into two groups: with and without hemolytic disease. Relation of laboratory parameters and immunohematological tests to severity of disease were studied. We did not analyze the maternal antibody titer or elusion test, and this was a limitation of the stud...

511 The attending physician in the nursery examines a jaundiced 20-h-old term, breastfed, white newborn. He is afebrile, nontoxic and well-nourished, weighs 3.8 kg and measures 50 cm, with a head circumference of 34 cm, but has a weak sucking reflex. Though icteric, he has no hepatosplenomegaly and no bleeding signs. His white blood cell count is 11,100 with a normal differential. His hemoglobi...

I compared enzymic methods for total serum cholesterol as used with discrete (Du Pont aca and reagent packs) and continuous-flow (Boehringer Mannheim reagents and the Technicon AuotAnalyzer I) analysis of normal, icteric, and lipemic sera. The regression equation for 24 clear, non-icteric sera was: y (continuous flow) = 0.944x (aca) + 10.69; r = 0.971, Syx +/- 53.7 mg of cholesterol per liter. ...