نتایج جستجو برای: ibritumomab tiuxetan

تعداد نتایج: 246  

Journal: :iranian journal of nuclear medicine 2012
shokrollah farrokhi mohammad ravanbod shahram amiri iraj nabipour majid assadi

the principle of cancer immunotherapy includes various methods of manipulations to influence immune responses against tumors in both humans and animals. this advanced technology of hybridoma production provided the necessary skills to efficiently produce highly specific monoclonal antibodies (mab). radioactively-tagged antibodies which are applied in radioimmunotherapy (rit), can target adjacen...

Journal: :Blood 2003
Bruce D Cheson

Enthusiasm for the use of monoclonal antibodies, such as rituximab, has markedly changed the approach to patients with non-Hodgkin lymphomas (NHLs). Nevertheless, more effective therapies are needed. Radioimmunotherapy as a form of targeted radiation therapy may add significantly to our therapeutic options. Yttrium Y 90 ibritumomab tiuxetan, recently approved by the Food and Drug Administration...

2014
Arne Kolstad Anna Laurell Mats Jerkeman Kirsten Grønbæk Erkki Elonen Riikka Räty Lone Bredo Pedersen Annika Loft Trond Velde Bogsrud Eva Kimby Per Boye Hansen Unn-Merete Fagerli Herman Nilsson-Ehle Grete Fossum Lauritzsen Anne Kristine Lehmann Christer Sundstrom Elisabeth Ralfkiaer Mats Ehinger Jan Delabie Hans Bentzen Jukka Schildt Kamelia Kostova-Aherdan Henrik Frederiksen Peter de Nully Brown Christian H. Geisler

Nordic MCL3 study: Y-ibritumomab-tiuxetan added to BEAM/C in non-CR patients before transplant in mantle cell lymphoma Arne Kolstad, Anna Laurell, Mats Jerkeman, Kirsten Grønbæk, Erkki Elonen, Riikka Räty, Lone Bredo Pedersen, Annika Loft, Trond Velde Bogsrud, Eva Kimby, Per Boye Hansen, Unn-Merete Fagerli, Herman Nilsson-Ehle, Grete Fossum Lauritzsen, Anne Kristine Lehmann, Christer Sundstrom,...

Journal: :Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2016
Jew Win Kuan Chiong Soon Law Xiang Qi Wong Ching Tiong Ko Zool Hilmi Awang Lee Ping Chew Kian Meng Chang

Radioimmunotherapy is an established treatment modality in Non-Hodgkin's lymphoma. The only two commercially available radioimmunotherapies - (90)Y-ibritumomab tiuxetan is expensive and (131)I-tositumomab has been discontinued from commercial production. In resource limited environment, self-labelling (131)I-rituximab might be the only viable practical option. We reported our pioneer experience...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2008
Samuel A Jacobs Steven H Swerdlow Jeffrey Kant Kenneth A Foon Rachel Jankowitz Stephanie R Land Nicholas DeMonaco Judith Joyce Jennifer L Osborn Terry L Evans Patricia M Schaefer The Minh Luong

PURPOSE Radioimmunotherapy has been approved for relapsed follicular lymphoma (FL), including rituximab-refractory FL. This study was designed to determine the CR rate with short-course chemoimmunotherapy with cyclophosphamide, doxorubicin, vincristine, prednisone, and rituximab (CHOP-R) followed by 90-Y ibritumomab tiuxetan (RIT) with extended rituximab as first-line treatment. EXPERIMENTAL ...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009
Heather A Jacene Ross Filice Wayne Kasecamp Richard L Wahl

UNLABELLED We retrospectively evaluated 18F-FDG PET/CT for monitoring the response of non-Hodgkin's lymphoma to radioimmunotherapy. METHODS A total of 33 clinical patients received 131I-tositumomab (n=23) or 90Y-ibritumomab tiuxetan (n=10) and underwent 18F-FDG PET/CT scans before radioimmunotherapy and at 12 wk after radioimmunotherapy. A third scan was performed on 13 patients at 24 wk afte...

Journal: :Current drug delivery 2011
Hong Song George Sgouros

Radioimmunotherapy of solid tumors remains a challenge despite the tremendous success of ⁹⁰Y ibritumomab tiuxetan (Zevalin) and ¹³¹I Tositumomab (Bexxar) in treating non-Hodgkin's lymphoma. For a variety of reasons, clinical trials of radiolabeled antibodies against solid tumors have not led to responses equivalent to those seen against lymphoma. In contrast, promising responses have been obser...

2007
Franck Morschhauser Tim Illidge Damien Huglo Giovanni Martinelli Giovanni Paganelli Pier Luigi Zinzani Simon Rule Anna Marina Liberati Noel Milpied Georg Hess Harald Stein Joachim Kalmus Robert Marcus

1Department of Hematology, Centre Hospitalier Universitaire (CHU) Lille, France; 2Christie Hospital, Manchester University, United Kingdom; 3Nuclear Medicine Division, European Institute of Oncology, Milan, Italy; 4Institute of Hematology “Seràgnoli,” University of Bologna, Italy; 5Derriford Hospital, Plymouth, United Kingdom; 6Policlinico Monteluce, Perugia, Italy; 7University Hospital of Bord...

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