نتایج جستجو برای: hypoglycemic effect
تعداد نتایج: 1647289 فیلتر نتایج به سال:
BACKGROUND The aqueous extract of Cucurbita ficifolia (C. ficifolia) fruit has demonstrated hypoglycemic effect, which may be attributed to some components in the extract. However, the major secondary metabolites in this fruit have not yet been identified and little is known about its extra-pancreatic action, in particular, on liver carbohydrate metabolism. Therefore, in addition to the isolati...
OBJECTIVE To evaluate glycemic control, hypoglycemic events, and quality of life in patients treated with continuous subcutaneous insulin infusion (CSII) and multiple daily insulin injection (MDI), with insulin lispro as the principal insulin. RESEARCH DESIGN AND METHODS This clinical trial enrolled 27 patients with type 1 diabetes. They were randomly assigned to CSII (n = 13) or MDI (n = 14)...
The initial observation of Cochrane, Payne, Simpkiss and Woolf, who described the hypoglycemic effect of L-leucine in certain patients with idiopathic infantile hypoglycemia (1), has been repeatedly confirmed. (2-6). L-leucine has also produced a hypoglycemic effect in certain patients with functioning islet cell tumors of the pancreas (7). Not all patients with these clinical syndromes respond...
TGR5 activation of enteroendocrine cells increases glucagon-like peptide 1 (GLP-1) release, which maintains glycemic homeostasis. However, TGR5 activation in the gallbladder and heart is associated with severe side effects. Therefore, intestinally-targeted TGR5 agonists were suggested as potential hypoglycemic agents with minimal side effects. However, until now no such compounds with robust gl...
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