OBJECTIVE Changes in the plasma aldosterone concentration (PAC) and the plasma renin activity (PRA) have not been extensively studied in women with twin pregnancies. METHODS The PAC and PRA levels were determined during the second and third trimesters and on postpartum day 3 in 14 normotensive women with twin pregnancies and 80 normotensive and 7 preeclamptic women with singleton pregnancies....

BACKGROUND Hypertensive disorders represent the most common medical complications of pregnancy with a reported incidence between 5 and 10%. The disorders are major causes of maternal and perinatal morbidities and mortalities. This study was conducted to determine the pattern and outcomes of pregnancies complicated by hypertensive disorders. METHODS Hospital based cross-sectional study was con...

STUDY QUESTION Does preconceptionally started low-dose aspirin prevent hypertensive pregnancy complications and preterm delivery in IVF patients? SUMMARY ANSWER The current data do not support the use of preconceptionally started low-dose aspirin treatment for the prevention of hypertensive pregnancy complications and preterm delivery in IVF women. WHAT IS KNOWN ALREADY Studies starting low...

An inverse association between birth weight and systolic blood pressure was first noted by Barker et al.1 Since then experimental studies have not only substantiated this finding but also provided insight into the potential mechanisms by which adverse influences during critical periods of fetal life lead to increased blood pressure and cardiovascular risk.2 Recent studies indicate that early po...

Aims: Preeclampsia is a hypertensive disorder of human pregnancy and a leading cause of premature delivery and fetal growth retardation. The purpose of this study was to evaluate the expression of heat shock protein 70 (HSP70), both constitutive (HSC70) and induced (HSP70) forms, along with oxidative stress status in the placental tissues of normotensive (control group) and preeclamptic pregnan...

The prevalence of premature cardiovascular diseases (CVD) is increased in women with a history of maternal placental syndromes, including pregnancy-associated hypertensive disorders (eg, preeclampsia), fetal growth restriction, and placental abruption. Whereas previous studies have shown a high prevalence of CVD risk factors after pregnancies complicated by preeclampsia, this has not been studi...

OBJECTIVE Small for gestational age (SGA) is associated with increased neonatal morbidity and mortality. At present, evidence on whether these pregnancies should be managed expectantly or by induction is lacking. To get insight in current policy we analysed data of the National Dutch Perinatal Registry (PRN). METHODS We used data of all nulliparae between 2000 and 2005 with a singleton in cep...

background: a recent study at the maroua provincial hospital revealed that hypertension in pregnancy was the first cause of maternal death, representing 17.5% of the 63 maternal deaths recorded between 2003 and 2005. knowing little about the causes, this study was to identify the possible risk factors for hypertensive disorders in pregnancy. methods: this case-control study was-done at the maro...