نتایج جستجو برای: hyperoxaluria
تعداد نتایج: 893 فیلتر نتایج به سال:
Studies from this laboratory in rats, cats, and monkeys’ have shown that vitamin B6 deficiency is accompanied by a marked increase in endogenous urinary oxalate excretion (1, 2). Studies of oxalate formation are of interest because of the importance of oxalate in urinary calculi (3) and in the genetic disorder, primary hyperoxaluria (4). In this paper alterations caused by vitamin Bg deficiency...
n engl j med 369;22 nejm.org november 28, 2013 2163 and its soluble salts are toxic before conversion to calcium oxalate endogenously remains unclear. Although the depiction of the metabolism of glyoxylate in Figure 1 of the article is correct, the figure does not show the generation of oxalate. The legend states that in hyperoxaluria types 1 and 2, accumulated glyoxylate is converted to oxalat...
CFEX (chloride/formate exchanger; Slc26a6) is an important anion exchanger of chloride, bicarbonate, oxalate (OX), formate, and hydroxyl ions in kidneys, liver, and the small intestine. Studies on CFEX-knockout mice indicated a possible role of CFEX in the development of hyperoxaluria and OX urolithiasis/nephrolithiasis, which in humans is more frequent in men. Here we studied the expression of...
in this paper we will present four cases of primary hyperoxaluria. all patients had a significant past medical history of polyuria (with or without microscopic hematuria) and polydypsia. all patients had a family history of their parents being cousins. initial evaluation of all patients by ultrasound and plain abdominal films revealed nephrocalcinosis. their clinical courses showed gradual loss...
Calcium oxalate monohydrate (COM) crystals are the commonest component of kidney stones. Oxalate and COM crystals in renal cells are thought to contribute to pathology via prooxidant events. Using an in vivo rat model of crystalluria induced by hyperoxaluria plus hypercalciuria [ethylene glycol (EG) plus 1,25-dihydroxycholecalciferol (DHC)], we measured glutathione and energy homeostasis of kid...
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