Medicinal plants play a key role in preventing various diseases. Hyperlipidemia is a major contributor to the pathogenesis of cardiovascular diseases. The purpose of the present study was to assess the effect of aqueous extract of Carum carvi seeds in diet induced hyperlipidemia in rats. 2% cholesterol diet were given to rats for six weeks and rats showed high lipid levels were included in the ...

Abstract Background Atherosclerosis is arteries’ thickening and stiffening condition manifested due to plaque formation by oxidized-LDL of abundant deranged lipid metabolism. Traditionally, Melastoma malabathricum Linn (MM) leaves are used for anti-diabetics, abdominal problems, high blood pressure. The current experiment unveils the potency ethanol, acetone, water MM extracts as antibacterial ...

To evaluate the clarithromycin pharmacokinetics after atorvastatin single and repeated dose administration in induced hyperlipidemic Wistar rats. A standard cholesterol diet (2% cholesterol) was used to induce hyperlipidemia and feed was given to rats for 6-8 weeks. Group’s allocation as follows: G1-G3: Induced hyperlipidemic rats pretreatment of atorvastatin as a single dose followed by clarit...

We describe a simple system for the preparation of a hyperlipidemic control serum. Beta- and pre-beta-lipoproteins are removed from the serum and prepared as a stable diluent; the extracted serum is then lyophilized. Upon addition of the lipoprotein diluent, which was observed to contain only liproprotein and sodium bicarbonate, the serum reconstitutes rapidly, usually within 5 min. By a suitab...

About 10 years ago, Furchgott and Zawadzki2 /... made a remarkable observation that helped .Lk.clarify variable effects of acetylcholine on arterial tone. They demonstrated that isolated arteries relaxed in response to acetylcholine and other endogenous vasoactive agents only in the presence of an intact endothelium and postulated that endothelial cells released a diffusible vasodilator princip...

Inappropriate nutrition and a sedentary lifestyle can lead to obesity, one of the most common risk factors for several chronic diseases. Although regular physical exercise is an efficient approach improve cardiometabolic health, exact cellular processes are still not fully understood. We aimed analyze morphological, gene expression, lipidomic patterns in liver adipose tissues response exercise....

background: coronary artery diseases are one of the most important issues in health and social problems. one of the amendable risk factors in development of these diseases is high cholesterol which can be modified through correction of lifestyle (diet change, playing sports, and usage of lipid‑lowering drugs). patients’ compliance to therapeutic programs is the most important element to achieve...