CLINICAL interest in hyperbaric oxygenation is recent, buit scientific curiosity abouit high-pressuire environment dates back to ancient times. Alexander the Great of Macedoinia was the earliest hyperbaric investigator of whom we have recorded evidence.' 2 He suirveyed the ocean depths in a glass and animal skin diving-bell (fig. 1). Among his most remarkable observations was a fish of such ext...

PURPOSE To evaluate the effect of hyperbaric oxygen therapy on the survival and weight of rats submitted to subtotal splenectomy and on the viability and growth of the inferior pole. METHODS Forty Wistar rats underwent subtotal splenectomy with preservation of the inferior pole and distributed into two groups: Group A (n=20) - not treated with hyperbaric oxygen, Group B (n=20) – treated with ...

PURPOSE To research the hyperbaric oxygen therapy effects on rats' livers and spleens. METHODS 30 adult male Hotzman rats were used, being randomly distributed, by raffle, into 2 groups of 15 animals each: group 1 - control; group 2 - hyperbaric oxygen therapy. Group-2 animals underwent hyperbaric oxygen therapy for 120 minutes daily, 90 minutes of which were under pressure of 2.5 atmospheres...

We describe a case in which hyperbaric oxygen therapy was used to salvage ischemic skin flaps after nipple-sparing mastectomy.

Mucormycosis is an uncommon acute invasive fungal infection that affects immunocompromised patients. It progresses rapidly and has poor prognosis if diagnosed late. Early detection, control of the underlying condition with aggressive surgical debridement, administration of systemic and local antifungal therapies, hyperbaric oxygen as adjunctive treatment improves prognosis and survivability.

The recently issued "Croatian List of Indications for Hyperbaric Oxygen Treatment" (HBO2T) includes indications from the Undersea and Hyperbaric Medical Society List of Indications and the European Consensus List of Indication for Hyperbaric Oxygen, but also several considered by many as "off-label." Now approved by Croatian national health authorities, these indications are no longer "off-labe...

[Purpose] To observe the effect of combined hyperbaric oxygen therapy on patients with post-stroke depression. [Subjects] Ninety patients with post-stroke depression were randomly divided into 3 groups: fluoxetine treatment group (n = 30), hyperbaric oxygen therapy group (n = 30), and hyperbaric oxygen combined treatment group (n = 30). [Methods] Fluoxetine treatment group received anti-depress...