The anaerobic incorporation of 32P into ATP by the tapeworm Hymenolepis diminuta was studied in the presence and absence of uncouplers of oxidative phosphorylation and anticestodal agents. Low concentrations of all compounds tested inhibited this incorporation. Under the anaerobic conditions employed, internal ATP concentrations remained constant in spite of the inhibition of the incorporation ...

The rapid elimination of the intestinal phase of Trichinella spiralis in NIH mice is associated with progressive inflammation of the intestinal tract. The non-specific effects of this inflammation were studied in mice concurrently infected with an unrelated parasite, Hymenolepis diminuta, which does not stimulate a visible inflammatory response but is also immunologically rejected by this strai...

Using immuno electron microscopy we have identified a number of calmodulin/calmodulin binding proteins distributed at various subcellular sites (Eastlake et al, 1994). Treatment of H. diminuta with trifluoperazine has potential cestocidal properties influencing both tegumental protein release, activity of calmodulindependent enzymes and the uptake of glucose (Branford White & Hipkiss, 1985; Hip...

Cestodes Since 1993 (1) several cases of sparganosis caused probably by Spirometra sp. have been observed. (5,6 and Samarasinghe S, personal communication). Bertiella studeri, an anoplocephalid tapeworm, is now recognised as a parasite acquired in areas where monkey reservoir hosts abound (7). As summarised by the present author (8) this cestode (Weerasooriya MV, Edirisinghe JS, personal commun...