Articular cartilage repair was followed for one year in skeletally mature dogs after destabilisation by anterior cruciate ligament transection of the stifle joint (CT), abrasion of the inferior medial condyle (ABR) to bleeding bone, or anterior cruciate transection followed by chondral abrasion (CT/ABR). ABR animals formed repair cartilage at the abrasion site (ABR and CT/ABR) at six months as ...

Background: It was well known that inhibitory effect of corticosteroids on cutaneous wound healing antagonized by the use of topical tretinoin and systemic vitamin A. However, the exact mechanism of this antagonistic interaction is not yet fully known. The aim of this study was to investigate the effects of topical tretinoin and adapalene application on tissue hydroxyproline content in corticos...

the present study was conducted to investigate the histological changes and wound healing effect of aqueous extract of elaeagnus angustifolia. after creating full-thickness skin wounds on the back of 45 male sprague-dawley rats they were randomly divided into three groups. treated group received the extract, positive control group were treated with mupirocin ointment 2% and control group did no...

Vitrosin, a fibrous protein obtained from the vitreous humor of the eye in the form of an indefinitely long fibril about 100 to 150 A in diameter, has been identified as a member of the collagen class of proteins. It is characterized by the collagen wide-angle x-ray diffraction pattern, and axial periodicity of about 640 A determined by electron microscopy and small-angle x-ray diffraction, an ...

A collagenous protein containing 15 to 19 per cent (12.9 to 16.7 per cent re&idues) hydroxyproline is found in capsules of rabbit lenses. The amount of this protein increases from about 0.6 to about 5 per cent by wet weight between the ages of 4 weeks and 1 year. The capsule contains also sialofucoglycoproteins and an acid mucopolysaccharide. The amount of the two carbohydrate polymers increase...

Serine:pyruvate/alanine:glyoxylate aminotransferase (SPT/AGT) is largely located in mitochondria in carnivores, whereas it is entirely found within peroxisomes in herbivores and humans. In rat liver, SPT/AGT is found in both of these organelles, and only the mitochondrial enzyme is markedly induced by glucagon. Although SPT/AGT is a bifunctional enzyme involved in the metabolism of both L-serin...

Objective-This study was conducted to evaluate the effect of co-administration of Aloe vera gel and cinnamon zeynalicum bark hydroethanolic extract on process of wound healing in diabetic mice model.Design- Experimental Study.Animals- Seventy-two male BALB/c mice.Procedures- A single full-thickness excisional wound was created on ba...

Three hydroxyproline-containing proteins secreted into the medium by human fibroblasts in culture were isolated and characterized. A minor fraction was identical to the collagen monomer. The major fraction was a form of procollagen, which contained, in addition to pro alpha and alpha chains, a component estimated to have a molecular weight of 250,000. This component was a dimer of pro alpha cha...