نتایج جستجو برای: hydroxy
تعداد نتایج: 31232 فیلتر نتایج به سال:
3-Hydroxy-2-pyrone is a valuable building block of many molecules. The syntheses until now proposed to prepare this compound are not ecofriendly and unsuitable for large scale productions. We report an easy gram preparation pyrone, by simple heating in water bio-based 6-caboxylic-3-hydroxy-2-pyrone derivatives. full process can be also performed telescopic reaction starting from galactaric acid...
The new major metabolite of @-acetylaminofluorene (AAF) in the rat, N-hydroxy AAF, was excreted in the urine as a conjugate in amounts that increased during car cinogenesis; the amount at 18 weeks was about 9 times that at 1@weeks. When 3methylcholanthrene, which greatly inhibits the carcinogenicity of AM?, was fed with AAF, the excretion of N-hydroxy-AAF remained low, while the excretion of 3a...
(7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid hydrazide (2) was prepared from (7-hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid ethyl ester (1) and 100% hydrazine hydrate. Compound 2, is the key intermediate for the synthesis of several series of new compounds such as Schiff's bases 3a-l, formic acid N'-[2-(7-hydroxy-2-oxo-2H- chromen-4-yl)acetyl] hydrazide (4), acetic acid N'-[2-(7-hydroxy-2-oxo-2...
Two new polyketides: 2Z-(heptadec-12-enyl)-4-hydroxy-3,4,7,8-tetrahydro-2H-chromen-5(6H)-one (1) and 2-(heptadec-12-enyl)-5-hydroxy-5,6,7,8-tetrahydrochromen- 4-one (2), together with eleven known compounds: 4-hydroxy-2-[(3,4-methylenedioxy- phenyl)tridecanoyl] cyclohexane-1,3-dione (3), oleiferinone (4), 4-hydroxy-2-[(3,4- methylenedioxyphenyl)undecanoyl]cyclohexane-1,3-dione (5), 4-hydroxy-2-...
The acetylation modification process of histone has an essential role in the epigenetic regulation gene expression. This is controlled by balance between deacetylases (HDAC) and acetyltransferases (HAT). HDACs are thought to be vital for cell function. Particularly, higher HDAC expression frequent various cancers, resulting dysregulation several target genes involved proliferation, differentiat...
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