Megalencephaly, polymicrogyria, polydactyly, and hydrocephalus (MPPH) syndrome has been recently recognized and is very rare. Each case reported so far has demonstrated hydrocephalus to varying degrees. We report an infant with MPPH syndrome, but lacking frank hydrocephalus. The additional finding of an abnormally elongated pituitary infundibulum has not been described in this syndrome and, alo...

OBJECTIVE A possible relationship between fibrosis along the route of cerebrospinal fluid (CSF) flow and the subsequent development of hydrocephalus has been indicated in previous studies. These changes in the fibrosis index may reflect the severity of hydrocephalus and could potentially become a diagnostic tool. The object of this study was to analyze the levels of procollagen type I C-termina...

A 1-year 9-month-old girl presented with achondroplasia. Serial magnetic resonance (MR) imaging demonstrated mild compression of the medulla oblongata by the occipital bone, macrocrania, and progressive hydrocephalus. Cerebrospinal fluid (CSF) flow study using MR imaging clearly demonstrated CSF flow disturbance at the cervicospinal junction. Foramen magnum decompression was performed for her h...

colloid cysts are mucous-filled masses with an outer fibrous layer. these cysts are rare developmental malformation and not a true neoplasm. they usually found incidentally and are asymptomatic; but in some cases may associate with rapid neurologic deterioration, herniation, and sudden death. recognition of this rare but important diagnosis may result in decreasing mortality. in this report, we...

Quadrigeminal arachnoid cyst are one of the rarest form intracranial cyst, this unique congenital malformation posses an special risk for hydrocephalus and neurological symptoms due to its proximity aqueduct brain stem. The treatment tends be surgical in cases when hypertension presents by hydrocephalus. Few non quadrigeminal with clinical follow up has been studied global literature . Here it’...

This article reviews our previous work on the dynamics of the intracranial cavity and presents new clinically relevant results about hydrocephalus that can be gained from this approach. Simulations based on fluid dynamics and poroelasticity theory are used to predict CSF flow, pressures and brain tissue movement in normal subjects. Communicating hydrocephalus is created in the model by decreasi...

Background: Tuberculous meningitis (TBM) is a severe form of extrapulmonary tuberculosis. One the most common complications TBM hydrocephalus, with higher risk mortality. This study aimed to evaluate outcome among patients or without hydrocephalus.Methods: was retrospective cross-sectional comparative analytical study. A total sampling employed based on number traceable resumes treated at Depar...

Although hydrocephalus affects approximately 80% of children with a posterior fossa tumor, its impact on neurodevelopmental outcomes remains unclear. We investigated the effects of hydrocephalus severity on the development of cognitive, motor, academic, and attention skills in 15 children with cerebellar injury after treatment for a tumor sustained during preschool years. Significant impairment...

Children with arrested, shunted, and no hydrocephalus were compared on verbal and nonverbal memory tasks assessing multiple components of memory. A gradient of severity was hypothesized, with the shunted hydrocephalus group expected to exhibit the most significant memory impairments and the arrested group expected to perform more poorly than children with no hydrocephalus. Etiologies of prematu...

The clinical features of patients with hydrocephalus include generalized reductions in coordinated motor and cognitive functions. Although some group similarities have been noted, the outward manifestations of this dysfunction vary in degree and character, with some subjects revealing no overt signs of the underlying hydrocephalus. A retrospective review of subjects with MR criteria of hydrocep...