In this study, we present a proposal for the physical and chemical quality control of the powder of the species T. parthenium (feverfew) and its hydroalcoholic extract obtained by percolation. The sesquiterpene lactone parthenolide, the main active compound of this plant, was quantifi ed by HPLC and its content was found to be 0.49% in the powder and 1.06% in the extract. The total content of f...

Different parts of the fruit of Punica granatum L. family Punicaceae cultivated in Egypt were extracted and standardized to be assessed for their anticancer and antioxidant properties. An HPLC method was modified and validated for standardization using ellagic acid (EA) as a marker. The 50% ethanol was proven to be a better solvent for extraction than the 70% ethanol, as the 50% hydroalcoholic ...

BACKGROUND Embelia schimperi has been used for the treatment of intestinal parasites especially tapeworm infestations for centuries in Ethiopia. However, there is lack of scientific based evidences regarding the efficacy, safety and phytochemical analysis of this plant despite its frequent use as an anthelmintic. This study has therefore evaluated the efficacy and acute toxicity of E. schimperi...

Hypercholesterolemia is a metabolic disorder characterized by a high concentration of cholesterol in the blood. Eryngium carlinae is a medicinal plant used to treat lipid diseases. The goal of this work was to evaluate, in a model of hypercholesterolemia in mice, the hypocholesterolemic effect of a hydroalcoholic extract of E. carlinae and its main metabolite, D-mannitol. Biochemical analyses o...

OBJECTIVES Diabetes mellitus is associated with biochemical, physiological and pathological alterations in the liver. The aim of this study was to investigate the effects of hydroalcoholic extract of Prangos ferulacea (L.) Lindle (P.f) on changes in rats´ liver structure and serum activities of alanin and aspartate aminotransferases after alloxan injection. MATERIALS AND METHODS In this study...

The present study was carried out to investigate the antidiabetic and antihyperlipidemic properties of hydroalcoholic extract of Peganum harmala in streptozotocin-induced diabetic male rats. In an experimental study, 64 normal Wistar albino male rats (200-230 g) were randomly divided into 8 groups. Control and diabetic rats were treated with normal saline and three different doses (30, 60, and ...

OBJECTIVE To evaluate the effect of different fractions of Black Maca (Lepidium meyenii), obtained from the hydroalcoholic extract, on spermatogenesis. DESIGN Animal study. SETTING Animal and laboratory facilities at a university. ANIMAL(S) Forty two adult male rats from the Holtzman strain (3 months old). INTERVENTION(S) Hydroalcoholic extract of Black Maca was partitioned with the fol...

based on experiments showing immunomodulatory effects of garlic (allium sativum l.), we sought to see whether allium hirtifolim boiss., belonging to the same genus of garlic, has any effect on immune responses. hydroalcoholic extract and polyphenolic fraction of a. hirtifolium bulbs were prepared. allicin (diallyl thiosulfinate), a biologically active component, was identified in plant bulbs by...

hydroalcoholic extract of pycnocycla spinosa has spasmolytic action in vitro . at oral dose of 250 m g/kg it inhibits castor oil induced diarrhea in mice. if p. spinosa extract has no serious adverse effect, it would be a good alternative medicine for treatment of diarrhoea and abdominal spasm. in this research, overall systemic effect of p. spinosa extract on mice behavior and reaction was inv...

introduction: the aim of the study was to investigate the effects of curcuma longa (c. longa) extract on adriamycin-induced hepatotoxicity in rat. methods: animals were divided in six groups: control (co), adriamycin (adr), adriamycin with vitamin c (adr+vitc), vitamin c (vit c), c. longa with adriamycin (cl+adr) and without adriamycin (cl-adr). hepatotoxicity was induced by adriamycin 5mg/kg a...