in order to determine the vector of visceral leishmaniasis in the endemic focus of fars province in southern iran, collection and dissection of sand- flies were carried out in the town of ghjr in firooz - abad district. a total of 270 sand- flies were dissected. they consisted of ph. alexandri, ph. sergenti ph. papatasi and ph. major. five out of 150 ph. major was found infected with promastigo...

Visceral leishmaniasis is a severe and potentially fatal vector-borne disease. The most typical symptoms are fever, hepatosplenomegaly, weight loss, bleeding and bacterial infections. Neurological changes are rarely reported. This paper describes a child who presented with neurological signs as the first symptoms of leishmaniasis; tone was diminished and tremors in the extremities were observed...

Leishmaniasis, an infectious disease endemic in tropical, Asian and southern European countries, is caused by obligate intramacrophage protozoa and is transmitted through the bite of infected female sandflies. More than 20 leishmanial species are responsible for four main clinical syndromes: cutaneous leishmaniasis; mucocutaneous leishmaniasis; visceral leishmaniasis, also known as kala-azar, a...

Post Kala Azar Dermal Leishmaniasis (PKDL) is an unusual dermatosis caused by a parasite Leishmania donovani (LD). It occurs between six months and five years of following an attack of Visceral Leishmaniasis (VL) / Kala Azar (KA). As a recurrence of VL, it keeps appearing on the skin of patient even after 20 years of partial treatment, inadequate treatment and in untreated cases. We here 4 case...

Leishmaniasis is an infectious disease caused by protozoa of the genus Leishmania transmitted by insects of the genus Lutzomyia sp. or Phlebotomus sp. The main syndromes are cutaneous leishmaniasis, mucocutaneous leishmaniasis, visceral leishmaniasis (kala-azar) and post-kala-azar dermal leishmaniasis. This article reviews kidney involvement in cutaneous and visceral leishmaniasis, highlighting...

BACKGROUND Visceral leishmaniasis is a parasitic disease associated with high mortality. The most important foci of visceral leishmaniasis in Ethiopia are in the Northwest and are predominantly associated with high rates of HIV co-infection. Co-infection of visceral leishmaniasis patients with HIV results in higher mortality, treatment failure and relapse. We have previously shown that arginase...

Canine leishmaniasis is a chronic parasitic disease transmitted by small bloodsucking insects. Clinically, affected patients present with progressive wasting, slight or marked reduction in appetite, lymphadenomegaly, splenomegaly, and cutaneous lesions (e.g., dry desquamation [dry seborrhea], ulcers, nodules). A correct diagnosis is based on specific serologic and molecular tests and nonspecifi...

The authors report the identification of Leishmania strains isolated from the Centre and the South of Tunisia. 266 strains were isolated between 1998 and 2006 from human (n=221 strains) and dogs (n=45 strains) hosts. The isoenzymatic identification exhibits the presence of in total five zymodemes belonging to three Leishmanio complexes: Leishmania infantum, L. major and L. killicki. All strains...

BACKGROUND The only oral drug available for the treatment of leishmaniasis is miltefosine, described and approved for visceral leishmaniasis in India. Miltefosine is under evaluation for the treatment of cutaneous leishmaniasis in the Americas although its efficacy for the treatment of human visceral leishmaniasis caused by Leishmania infantum chagasi has not been described. Drug efficacy for v...

background: visceral leishmaniasis (vl) is one of the most important parasitic diseases endemic in northwestern and southern areas of iran. the aim of the pre-sent study was to review the records of children hospitalized with vl in order to characterize the clinical features of children as well as laboratory finding in chil-dren medical center hospital, tehran, iran. methods: the medical record...