conclusions simpleprobe® real-time pcr is a fast and accurate technique qualified to detect vkorc1 and cyp2c9 snps. these results encourage taking further steps towards using vkorc1 and cyp2c9 allelic screening to prevent clinical complications due to resistance or sensitivity to warfarin as well as anti-coagulant dose adjustment. results the allelic frequencies for vkorc1 c1173t (cc, ct, tt) w...

conclusions the quite sensitive in-house taqman real time rt-pcr assay was able to detect and quantify all four main hcv genotypes prevailing around all geographical regions of iran. results the lower limit detection of this in-house hcv real-time rt-pcr was determined as 100 rna copies/ml. inter- and intra-assay coefficient of variation (cv) of this in-house hcv real-time rt-pcr ranged from 0....

background legionellaceae contains legionella genus with over 52 species and 64 serogroups. it is one of the most important causes of respiratory disease in human. more than 30% of hospital-acquired pneumonia is caused by legionella. ventilator-associated pneumonia (vap) is an infection acquired in hospital wards, particularly in intensive care unit (icu). this disease approximately affects 9% ...

 The final goal of this research is to analyze the human visual and force sensory feedback integration related to a manipulation task and build a control model of a human operator. In this primary work the reaction time was measured to determine the time lag constant of each subject. During the measurement of the reaction time, fluctuations in the pupil size and heart beat were verified and th...

The design and implementation of a wearable system to estimate the human reaction time (HRT) to visual stimulus based on two identical wireless motion sensors are described. Each sensor incorporates a motion sensor (gyroscope), a processor and a transceiver operating at the industrial, scientific and medical frequency of 2.45 GHz. Relevant tests to estimate the HRT are performed in two differen...

Introduction: IAChE (acetylcholinesterase) is one of the plasma’s enzymes that plays a crucial role in nervous signal transduction in synapses and is responsible for the hydrolysis of Ach. Material & Method: We investigated three methods for the determination of AChE in human blood serum, using three different assays. Michel methods are based on the measurement of hydrogen ion produced in pro...

the ataxia telangiectasia mutated gene (atm), candidate for breast cancer susceptibility gene, encode a 350-kda protein belongs to the core components of dna-damage response machinery. female at carriers have at least 5-fold increase risk for breast cancer. reduction in atm expression is shown in multiple studies in breast tissues. we aimed to perform a research to measure the atm mrna expressi...

backgoround: plant diseases, caused by a wide range of phytopathogenic fungi, could be managed using of trichoderma sp, as a biocontrol agent. cell wall degrading enzymes like chitinase from t. harzianum are important means for fungal pathogen inhibition. overexpression of these chitinase enzymes can improve the antagonistic potential of trichoderma sp. strains. objectives: this study aimed to ...

This paper addresses the question how to compare reaction times computed by a computational model of speech comprehension with observed reaction times by participants. The question is based on the observation that reaction time sequences substantially differ per participant, which raises the issue of how exactly the model is to be assessed. Part of the variation in reaction time sequences is ca...