The p53 gene is one of the most extensively studied human genes because of its role as a tumor suppressor. A common polymorphism of the p53 gene at codon 72 has been associated with human cancer susceptibility and prognosis. Human papilloma virus (HPV) has also been suggested to be involved in the pathogenesis of esophageal cancers. In this study, we investigated codon 72 polymorphism in 40 eso...

human papillomavirus (hpv) is one of the most common causes of sexually transmitted diseases worldwide and is the etiological agent of cervical and other anogenital malignancies. since hpvs have been shown to possess oncogenic potential, an association between hpv infection and prostatic cancer (pca) has been suggested. there are conflicting reports on the impact of hpv infection on the develop...

conclusions cervical cancer screening, comprising of both pap test and hpv testing, is an essential part of the routine health care for women as it can facilitate the detection of abnormal cervical cells. hpv infection can produce abnormal pap test results; also, certain types of hpv are associated with cancer. therefore, it is important to diagnose abnormal cervical tissues before the developm...

  Background and Objective: To estimate the risk of human papilloma virus (HPV) infection for cervical malignancies, we conducted a case-control study in southern Iran (Hormozgan province). Materials and Methods: For this purpose,52 paraffin embedded blocks with exact diagnosis of cervical carcinoma(50 carcinomas and 2 carcinomas in situ) from 2001 to 2006 and 52 praffin embedded blocks of ce...

conclusions this study describes robust information on the distribution of hpv genotypes among iranian women with and without cervical lesions. the present data may be of importance for designing future public health strategies, including hpv vaccination programs. results in total, hpv infection was detected in 45.4% of the cases. the most common high-risk hpv (hr-hpv) genotype was hpv-16 (32.8...

background: in 1970, human papillomavirus (hpv) was introduced as the main etiologic factor of cervical carcinoma. since there is no possibility of detecting the virus and its subtypes using serological methods and cell culture, the molecular methods such as pcr have particular importance in accurate, early and definite diagnosis of the virus. so, in this research, our goal is to use a propriet...

Human papillomaviruses (HPVs) cause superficial epidermal infections and are only cleared if they trigger an immunological response. We analysed SNPs that had previously been investigated for association with HPV infection to determine whether play a role in the serological response cutaneous beta-HPVs Australian population. Serum samples from 1,142 participants were seropositivity against L1 p...

Background: Anogenital wart is a common sexually transmitted disease affecting both genders. The aim of this study was to evaluate human papilloma virus types of anogenital warts with Polymerase Chain Reaction (PCR). Method: 65 formalin fixed paraffin embedded (FFPE) tissue blocks of the anogenital warts obtained from the pathology lab of Loghman Hakim hospital were included in this study. Resu...

condyloma acuminatum, is a rare sexually transmitted disease. the virus responsible for condyloma is human papillomavirus. hpv-6 and hpv-11 are the most commonly detected hpv genotypes, but at least 20 other hpv genotypes have occasionally been found in genital wart tissue specimens. in fact genital hpv infection is common among sexually active populations. this disease may occur at any age aft...