نتایج جستجو برای: human itpa protein

تعداد نتایج: 2478083  

Journal: :Psycho-oncology 2013
Lena Heyn Arnstein Finset Hilde Eide Cornelia M Ruland

BACKGROUND To test the effect of Choice, an interactive tailored patient assessment (ITPA) tool on the number and types of symptoms addressed during consultations with cancer patients, cancer patients' active participation during consultation with clinicians, and clinicians' responses. METHOD A total of 193 consultations were audio taped and coded with the task-oriented part of Roter Interact...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس - دانشکده علوم پایه 1391

ms یک بیماری خودایمنی مزمن است که در آن میلین نورون های دستگاه عصبی مرکزی (cns) آسیب دیده و آکسون ها تخریب می شوند. تخمین زده می شود که حدود 5/2 میلیون نفر در سراسر جهان به ms مبتلا باشند. ایران در ناحیه ای با شیوع متوسط قرار دارد و آمار ابتلا به آن در کشور رو به افزایش می باشد. ms یک بیماری پیچیده است و تحت تأثیر عوامل محیطی و ژنتیکی متفاوتی می باشد. یکی از داروهایی که برای بیماران ms تجویز می...

Journal: :modares journal of medical sciences: pathobiology 2008
behrouz hassannia mehrdad behmanesh mohammad taghi akbari

objective: one of the most significant damages to the genetic material is oxidative deamination of dna and free nucleotides in the cell pool. incorporation of deaminated purine nucleotides such as inosine triphosphate (itp, ditp) into the dna can increase the frequency of base substitution mutation. it has been suggested that presence and accumulation of these rough nucleotides can lead to gene...

Journal: :hepatitis monthly 0
sheng-hung chen institute of clinical medical science, school of medicine, china medical university, taichung, taiwan; school of medicine, china medical university, taichung, taiwan; division of hepatogastroenterology, department of internal medicine, china medical university hospital, taichung, taiwan cheng-yuan peng school of medicine, china medical university, taichung, taiwan; division of hepatogastroenterology, department of internal medicine, china medical university hospital, taichung, taiwan; division of hepatogastroenterology, department of internal medicine, china medical university hospital, china medical university, taiwan. tel: +88-6422052121 hsueh-chou lai institute of clinical medical science, school of medicine, china medical university, taichung, taiwan; division of hepatogastroenterology, department of internal medicine, china medical university hospital, taichung, taiwan; college of chinese medicine, china medical university, taichung, taiwan wen-pang su division of hepatogastroenterology, department of internal medicine, china medical university hospital, taichung, taiwan chia-hsin lin division of hepatogastroenterology, department of internal medicine, china medical university hospital, taichung, taiwan yu-fen li institute of biostatistics, china medical university, taichung, taiwan

conclusions in patients with chc g1 and receiving combination therapy, itpa snp-based index was an accurate and practical solution for prediction of severe anemia. background single-nucleotide polymorphisms (snp) in the inosine triphosphate pyrophosphatase (itpa) gene correlate with ribavirin (rbv)-induced anemia in patients with chronic hepatitis c (chc) receiving combination therapy. managing...

2014
Ahmad Amanzada Armin D Goralczyk Lars Reinhardt Federico Moriconi Silke Cameron Sabine Mihm

BACKGROUND A decline in hemoglobin (Hb) concentration during antiviral therapy in chronic hepatitis C (CHC) is a serious side effect. It may compel to dose reduction or even termination of antiviral treatment. The activation of erythropoietin (EPO) synthesis as a physiological response to anemia and its relation to a genetic variation within the EPO gene has not been evaluated yet. METHODS Da...

2017
Jeongsoon Kim Hyewon Shin

Species identification of animal tissues in meat products is an important issue to protect the consumer from illegal and/or undesirable adulteration, for economic, religious and health reasons. For example, pork DNA was found in halal chicken sausages served in a primary school in Westminster, central London, the local authority had stated on 14 March 2015. PCR is one of the most widely used te...

Journal: :Journal of hepatology 2013
Monika Rau Felix Stickel Stefan Russmann Christine N Manser Philip P Becker Michael Weisskopf Johannes Schmitt Michael T Dill Jean-François Dufour Darius Moradpour David Semela Beat Müllhaupt Andreas Geier

BACKGROUND & AIMS In the last decade, pegylated interferon-α (PegIFN-α) plus ribavirin (RBV) was the standard treatment of chronic hepatitis C for genotype 1, and it remains the standard for genotypes 2 and 3. Recent studies reported associations between RBV-induced anemia and genetic polymorphisms of concentrative nucleoside transporters such as CNT3 (encoded by SLC28A3) and inosine triphospha...

Journal: :journal of biotechnology and health sciences 0
samiie pouragahi department of molecular medicine, school of medicine, qazvin university of medical sciences, qazvin, ir iran; department of bioinformatics, national institute of genetic engineering and biotechnology (nigeb), tehran, ir iran; department of pharmacology, cellular and molecular research center, school of medicine, qazvin university of medical sciences, qazvin, ir iran mohammad hossein sanati department of molecular genetics, national institute of genetic engineering and biotechnology (nigeb), tehran, ir iran mehdi sadeghi department of bioinformatics, national institute of genetic engineering and biotechnology (nigeb), tehran, ir iran marjan nassiri-asl department of pharmacology, cellular and molecular research center, school of medicine, qazvin university of medical sciences, qazvin, ir iran; school of medicine, qazvin university of medical sciences, qazvin, ir iran. tel: +98-2833336001, fax: +98-2833324971

conclusions the growth rate of information in bioinformatics databases could facilitate studies of live organisms prior to observation studies. two different protein classes could be causative agents of one disease. however, two related diseases from one disease group could consist of different protein classes. future research in the field of proteomics could allow modern insight to reshuffling...

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