Internet-Drafts are working documents of the Internet Engineering Task Force (IETF), its areas, and its working groups. Note that other groups may also distribute working documents as Internet-Drafts. Internet-Drafts are draft documents valid for a maximum of six months and may be updated, replaced, or obsoleted by other documents at any time. It is inappropriate to use Internet-Drafts as refer...

The tail domain of the intermediate filament (IF) protein vimentin is unnecessary for IF assembly in vitro. To study the role of vimentin's tail in vivo, we constructed a plasmid that directs the synthesis of a 'myc-tagged' version of the Xenopus vimentin-1 tail domain in bacteria. This polypeptide, mycVimTail, was purified to near homogeneity and injected into cultured Xenopus A6 cells. In the...

JNCI | Editorials 543 The majority of patients who are diagnosed with bladder cancer initially present with noninvasive disease ( 1 ). Nevertheless, 40% – 80% of patients diagnosed with superficial bladder cancers will experience a recurrence, including 10% – 25% of those with potentially lethal muscle-invasive disease, within the first 3 years after diagnosis ( 2 – 4 ). Current guidelines from...

s International, 55, AAT 9511231. Delquadri, J., Greenwood, C. R., Whorton, D., Carta, J., & Hall, R. V.(1986). Classwide peer tutoring. Exceptional Children, 52, 535–542.Elbaum, B., Vaughn, S., Marie, H., & Moody, S. W. (1999). Grouping prac-tices and reading outcomes for students with disabilities. ExceptionalChildren, 65, 399–415.Fuchs, D., Fuchs, L. S., Mathes, P. G....

Internet-Drafts are working documents of the Internet Engineering Task Force (IETF), its areas, and its working groups. Note that other groups may also distribute working documents as Internet-Drafts. Internet-Drafts are draft documents valid for a maximum of six months and may be updated, replaced, or obsoleted by other documents at any time. It is inappropriate to use Internet-Drafts as refer...

Cellular homeostasis in neurons requires that the synthesis and anterograde axonal transport of protein and membrane be balanced by their degradation and retrograde transport. To address the nature and regulation of retrograde transport in cultured sympathetic neurons, I analyzed the behavior, composition, and ultrastructure of a class of large, phase-dense organelles whose movement has been sh...

Amyloid plaques, a defining feature of Alzheimer’s disease (AD) brain pathology, have long been recognized to contain an extracellular aggregate of the β-amyloid peptide that is surrounded by microglia and an abundance of swollen axons (Terry et al., 1964; Itagaki et al., 1989; Tsai et al., 2004; Fiala, 2007; Condello et al., 2011). These axons contain a massive accumulation of organelles that ...

The purpose of this paper was to provide an overview of research in the area of goal setting and performance in sport and exercise settings. Much of the early research in goal setting has been conducted in industrial/organizational settings as it has only been in the last seven to ten years that researchers have begun to focus on goal setting in sport and exercise settings. This has often produ...

Central MessageAttrition after stage 2 Norwood has not changed in 30 years. Improved neonatal outcomes may have created a fragile subpopulation of patients who did survive earlier eras and remain at risk.See Article page 385. Attrition risk. See We continue to learn from the unique experience Children's Hospital Philadelphia's (CHOP) analysis their program for hypoplastic left heart syndrome, w...

Most of us struggle with our writing. We thrash and hack our way through paragraphs, writing and editing and rewriting until we think we’ve made some progress on that God-forsaken manuscript. The next morning we turn on the computer, read the file, and realize that our work of art is a muddled mess. We curse, hit the delete key, and start again. It can be a frustrating process, particularly for...