statement of problem: various factors are involved in causing inflammation following root canal treatment. controlling these factors may relieve the related pain. one of these factors is extrusion of debris beyond the apex. although debris extrusion happens in all instrumentation techniques, researchers have declared that in coronal flaring technique, there is minimum debris extrusion. purpose:...

although the majority of the patients with traumatic brain injury presents with injuries involving the extremities, there was a clear paucity of adequate experimental polytrauma models. to close this gap, we conducted several studies to establish two different polytrauma mice models including both closed and open traumatic brain injury. male c57bl mices with a mean weight of 23g were anesthetiz...