Drug eruptions are among the most common inflammatory diseases of the skin and also among those biopsied most often. Yet, the value of histopathologic examination of drug eruptions has often been disputed. One reason is that the spectrum of histopathologic changes in drug eruptions is broad. Nevertheless, each histopathologic pattern assumed by drug eruptions has a limited number of differentia...

PURPOSE Previous studies of cutaneous eyelid lesions have been retrospective using multiple contributing surgeons. The purpose of this study was to determine prospectively the accuracy of the clinical diagnosis of benign, premalignant, and malignant cutaneous eyelid lesions and to determine if all clinical diagnoses require histopathologic confirmation, or if an experienced clinician can reliab...

introduction: the aim of this study was to identify the reasons for failure in clinical, radiographic, and histopathologic diagnoses as well as their interactions with each other. methods: personal information and lesion characteristics of 51 patients with central or peripheral exophytic lesions were collected in mashhad dental school. specialists determined clinical and radiographic diagnoses ...

Report of Cases. Case 1. A 9-yearold white girl underwent excision of a small, rapidly growing, black pigmented lesion of the inferior palpebral conjunctiva and the adjacent margin of the right lower eyelid. The original histopathologic diagnosis was an active junctional nevus of the conjunctiva and eyelid margin. The lesion recurred 3 years later and was excised by a dermatologist who did not ...

Bednar tumor is a rare skin neoplasm, considered to be a pigmented variant of dermatofibrosarcoma protuberans. Diagnosis is confirmed through histopathologic examination and immunohistochemical evaluation. Bednar tumor is aggressive locally and recurrences are frequent, but metastases are rare. The most appropriate therapeutic procedure is Mohs' micrographic surgery. The case report presents a ...

The diagnosis of seborrheic keratosis is a clinical diagnosis. In a certain percentage of cases, differential diagnosis between seborrheic keratosis and malignant melanoma is difficult. We describe a case of regressing seborrheic keratosis simulating malignant melanoma. Clinical, dermoscopic and histopathologic examinations were performed for the occurrence of an asymmetric, irregularly demarca...

Report of Cases. Case 1. A 9-yearold white girl underwent excision of a small, rapidly growing, black pigmented lesion of the inferior palpebral conjunctiva and the adjacent margin of the right lower eyelid. The original histopathologic diagnosis was an active junctional nevus of the conjunctiva and eyelid margin. The lesion recurred 3 years later and was excised by a dermatologist who did not ...

Introduction: Glioblastoma multiforme (GBM) is the most common and aggressive primary malignant brain tumor found in adults. GBM has limited therapeutic options. Initial sampling establishes histopathologic diagnosis, identifies prognostic biomarkers, provides an opportunity for molecular profiling. By contrast, utility of repeat profiling recurrent not well established.

in riedel’s thyroiditis, a rare chronic inflammatory disease of thyroid gland, fine needle aspiration is usually non-diagnostic because most often only follicular cells are obtained and not the fibrous material characteristic of this type of thyroiditis. therefore the diagnosis is often only established by histopathologic study of the surgically obtained biopsy. the illustrated case is a 46-yea...