A conventional analytic model used for evaluating the performance of computer and communication systems accepts single values as model inputs and computes a single value for each performance measure of interest. However uncertainties regarding parameter values exist in diierent situations such as during early stages of system design. Although the clients in a system are statistically identical ...

There are situations in which it is necessary to combine samples obtained under different simulation conditions to determine properties (e.g. averages or PMFs) of the system under a single condition (which may not even be one of the conditions that were actually simulated). One example is the determination of a PMF to obtain accurate measures of a free energy barrier. If the barrier is substant...

A new technique for color reduction is presented, based on the analysis of the histograms of an image at different resolutions. Given an input image, lower resolution images are generated by using a scaling down interpolation method. Then, peaks and pits that are present in the histograms at all resolutions and dominate in the histogram of the input image at full resolution are taken into accou...

An approach for contrast enhancement utilizing multi-scale analysis is introduced. Sub-band coefficients were modified by the method of adaptive histogram equalization. To achieve optimal contrast enhancement, the sizes of sub-regions were chosen with consideration to the support of the analysis filters. The enhanced images provided subtle details of tissues that are only visible with tedious c...

The proliferative activity of human neoplasms may be an important determinant for therapeutic management. The advent of automated flow-through systems measuring cellular DNA content by means of fluorescence has considerably facilitated the analysis of cellular kinetics. Using a pulse cytophotometer ICP-11 (Phywe Co., Göttingen, Germany), three different fluorescent staining techniques for DNA h...

The first step required for many applications and algorithms is the segmentation or clustering of an image. This intuitively easy problem is actually very difficult for a computer to automatically perform. While having an effective solution to this problem would be valuable for all types of image processing, it would be especially useful in medical imaging. One method that addresses this proble...

Digital image watermarking is one of the most widely used techniques for protection of ownership rights of digital images. Its commercial applications range from copyright protection to digital rights management. However, although there have been numerous new proposed digital image watermarking techniques, most are not sufficiently robust against watermark attacks. With the main objective of fi...

We propose a new algorithm for solving the Weighted Histogram Analysis Method (WHAM) equations to estimate free energies out of a set of Monte Carlo (MC) or Molecular Dynamics (MD) simulations. The algorithm, based on free energy differences, provides a more natural way of approaching the problem and improves convergence compared to the widely used direct iteration method. We also study how par...