The main thrust for this work is the investigation and design of a positron emission tomography (PET) scanner based on new Lanthanum Halide scintillators. In three–dimensional (3-D) PET the major limitations are scanner dead-time and ability to reject randoms and scatter. Therefore, to reach the full potential of 3-D PET requires a scintillator with good timing resolution and good energy resolu...

Department of Physics of Molecular Imaging Systems, RWTH Aachen University, Germany In this work we present detailed characterizations of our preclinical high resolution PET/ MR insert based on the Hyperion-IID platform. The PET/MR insert consists of a ring of 10 singles detection modules, each comprising 2×3 scintillation detector stacks. Each detector stack features a 30×30 pixelated LYSO cry...

PET is a scanning technique in medical imaging based research. It allows us, for the first time, to measure in detail the functioning of distinct areas of the human brain while the patient is comfortable, conscious and alert. This work presents new super-resolution algorithm for improving the resolution in clinical positron emission tomography (PET) scanners. Super-resolution images were obtain...

Abstract Background Integrated whole-body PET/MR technology continues to mature and is now extensively used in clinical settings. However, due the special design architecture, integrated comes with a few inherent limitations. Firstly, lacks sensitivity resolution for focused organs. Secondly, broader access of has been significantly restricted its prohibitively high cost. The MR-compatible PET ...

Patient motion due to respiration can lead to artefacts and blurring in positron emission tomography (PET) images, in addition to quantification errors. The integration of PET with magnetic resonance (MR) imaging in PET-MR scanners provides complementary clinical information, and allows the use of high spatial resolution and high contrast MR images to monitor and correct motion-corrupted PET da...

BACKGROUND Plaque vulnerability to rupture has emerged as a critical correlate to risk of adverse coronary events but there is as yet no clinical method to assess plaque stability in vivo. In the search to identify biomarkers of vulnerable plaques an association has been found between macrophages and plaque stability--the density and pattern of macrophage localization in lesions is indicative o...

Potential evapotranspiration (PET) is a key parameter for calculating drought monitoring index that generally difficult to obtain. In addition, PET has low spatial resolution and can only be obtained at site-based point. Therefore, retrieving with high precision, resolution, less meteorological data becomes the focus of this paper. paper, high-precision high-spatial-resolution (HDM) model was e...

OBJECTIVE To design a novel ex-vivo acquisition technique to establish a common framework to validate different segmentation techniques for oncological PET images. To evaluate several automatic segmentation algorithms on this set of images. MATERIAL AND METHODS In 15 patients with cancer, ex-vivo PET studies of surgical specimens removed during surgery were performed after injection of (18)F-...