the present study was aimed to develop and validate a high performace liquid chromatography method for determination of thiocolchicoside and dexketoprofen trometamol in combined dosage form. the proposed hplc method utilizes an agilent eclipse c-8 column (5 µm, 250×4.6 mm) at ambient temperature. a 23 full factorial design was performed for optimization of mobile phase for separation of two dru...

an agar well diffusion bioassay method for determination of clarithromycin in human plasma, using micrococcus luteus atcc 9341 as the assay organism, was compared with a selective high-performance liquid chromatographic (hplc) method with uv detection. spiked plasma was used to prepare standard and control samples for both methods. the results of the bioassay analyses with spiked plasma samples...

carotenoids are red, orange and yellow pigments, which are widely distributed in fruit and vegetables. the aim of this research is to investigate the effect of conventional, high pressure and microwave cooking on the concentrations of β-carotene in carrot and sweet corn. raw carrots were washed, peeled and diced to a uniform size and then frozen at -70°c. sweet corn was also provided in a simil...

background aflatoxins are a group of very toxic compounds produced by a fungal species and are found in food products. aflatoxin m1 (afm1) is a type found in dairy products and resistant to pasteurization. afm1 can adversely affect hepatocytes in human and leading to various liver diseases. thus, it is essential to examine raw milk for the presence of afm1. conclusions according to the results ...

dispersive liquid-liquid microextraction method (dllme) combined with high-performance liquid chromatography-ultraviolet detection (hplc-uv) was used to determine thiamine (b1), nicotinamide (b3) and pyridoxine (b6) in sour cherry juice. this method was rapid, simple and sensitive. separation was accomplished using a c18 column. the optimum chromatographic conditions were found to be: mobile ph...

in this project, eggshell membrane was used as a solid phase extraction sorbent for extraction of morphine followed by hplc analysis. at first, raw eggshell membrane was used and then, because of low adsorption of morphine on untreated eggshell membrane (

silymarin is a mixture of flavonolignans from the seeds of silybum marianum (l.) gaertner,containing silybinin, isosilybinin, silydianin, silychristin and the dihydroflavonol of taxifolin. flavonolignancomponents are largely responsible for the medical benefits attributed to silymarin. the aim of this researchwas to study the variations in composition and content of flavonolignans of silymarin ...

background and objectives:drimia maritima (l.) stearn also known as squill is a medicinally important plant that has been used for various ailments such as dropsy, respiratory disorders, jaundice and epilepsy from ancient times. proscillaridin a is identified as one of the most effective compounds in the plant with remarkable pharmacological features including efficacy against congestive heart ...

The improvement in hyphenated analytical techniques has significantly widened their applications to the analysis of biomaterials. In this article, we discuss recent advances in applications of hyphenated chromatographic techniques including capillary electrophoresis to the analyses of biological samples. As tools of separation, gas chromatography, high-performance liquid chromatography and capi...