Abstract— Full-3D particle-in-cell Monte Carlo simulation of a new scheme electron radiotherapy based on acceleration by high-power femtosecond laser pulse propagating in plasma sub-critical density the relativistic self-trapping regime (V. Yu. Bychenkov et al., Plasma Phys. Control. Fusion 61 , 124004 (2019)) was carried out. Based results distribution energy deposited bunches accelerated such...

Introduction: Esophageal cancer is one of the most frequently occurring cancers in Iran and having a  high  incidence  rate  among  other  countries.  Radiotherapy  is  one  of  the  three  methods  (surgery,  radiotherapy and chemotherapy) for radical or palliative treatment of esophageal cancer. In this method  of treatment, the organs such as heart and spinal cord are regarded as organs at r...

Megavoltage electron beams represent an important treatment modality in modern radiotherapy, often providing a unique option in the treatment of superficial tumours (less than 5 cm deep). Electrons have been used in radiotherapy since the early 1950s, first produced by betatrons and then by microtrons and linacs. Modern high energy linacs typically provide, in addition to two megavoltage photon...

When high-energy photon beams are used for irradiation in radiotherapy, neutrons that are the result of photonuclear reactions create activation products that affect the occupational dose of radiotherapy staff. For the assessment of activation products in situ gamma spectroscopy was performed parallel to dose-rate measurements following irradiation, by using a high-energy photon beam from a lin...

High-energy X-rays offer several advantages over lower energy photons including: lower skin dose, higher depth dose, smaller scattered dose to tissues outside the target volume and less rounded isodose curves. These advantages in physical dose distributions have led to significant improvements in clinical radiotherapy, and high energy linear accelerators are now a standard fixture of radiothera...

Introduction Accurate estimation of the skin-absorbed dose in external radiation therapy is essential to estimating the probability of secondary carcinogenesis induction Materials and Methods Electron contamination in prostate radiotherapy was investigated using the Monte Carlo (MC) code calculation. In addition, field size dependence of the skin dose was assessed. Excess cancer risk induced by...

Radiotherapy has a universal and predictable mode of action, that is, a physical mode of action consisting of the deposit of a dose of energy in tissues. Tumour cell damage is proportional to the energy dose. However, the main limitation of radiotherapy is the lack of spatial control of the deposition of energy, that is, it penetrates the healthy tissues, damages them and renders unfeasible del...

the radiobiological effects of high atomic number and energy (hze particles) ion beams are of interest for radioprotection in space and tumor radiotherapy. space radiation mainly consists of heavy charged particles from protons to iron ions, which is distinct from common terrestrial forms of radiation. hze particles pose a significant cancer risk to astronauts on prolonged space missions. with ...

Background: Cancer is a complex disease with high rate of mortality. At present, Radiation therapy is one of the most common procedures to overcome this situation. The deficiency of conventional method is the lack of fatal dose transmission into the malignant tissue. Hence, uncertain dose may cause regeneration of cancer cells, and relapse of the disease and invasion of the cancer cells to ...