easily degradating and various isomeric forms of rapamycin (sirolimus) face the determination of this compound to many challenges. in this study, we developed and validated the isocratic reversed phase high performance liquid chromatographic (rp-hplc) method for rapamycin. separation was performed on a c8 column (mz, 15 × 4.6 mm, 5 µm particle size) using methanol:water (80:20 v/v) as the mobil...

background: to investigate the expression of tnf-α, il-6, il-10 in the plasma of patients with lung cancer who received radiation therapy (rt), and to analyze the correlation between these cytokines and radiation pneumonitis (rp). materials and methods: patients with lung cancer who received 3d-crt in our hospital were prospectively evaluated. circulating cytokine levels were measured with elis...

the development of a number of different rapid prototyping (rp) technologies with wide-ranging capabilities, features and applications has created the problem of selecting an appropriate rp system for engineering educational institutions as well as manufacturing organizations intending to adopt this new technology. this paper presents an rp decision support system (rp dss) for ranking and selec...

A simple, rapid, specific, accurate and precise RP-HPLC method was developed for the simultaneous estimation of Lafutidine Rabeprazole Sodium in combined dosage form. Hi Q sil C-8 Column (250 mm × 4.6 mm, 5 μm) Isocratic mode with mobile phase containing Acetonitrile : Phosphate Buffer (70:30 v/v) pH 7.3 used. The flow rate 1.0ml/min effluents were monitored at 230 nm. retention time found to b...

BACKGROUND Macrophages derived foam cells are key factors in the maladaptive immune and inflammatory response. OBJECTIVES The study of the cholesterol homeostasis and the molecular factor involved in these cells is very important in understanding the process of atherosclerosis and the mechanisms that prevent its occurrence. MATERIALS AND METHODS This experimental study investigated the effe...