Radioiodinated human FSH (‘?-hFSH) was used to study the specificity of the gonadotropin binding sites of various reptilian, avian, and mammalian gonadal tissues by examining competitive interactions with several nonmammalian gonadotropins. All preparations of nonmammalian gonadotropins showed some activity in these radioligand assays, but wide variations in activities were evident depending on...

24 Caulobacter crescentus cells adhere to surfaces using an extremely strong polar 25 adhesin called the holdfast. The polysaccharide component of the holdfast is 26 comprised in part of oligomers of N-acetylglucosamine. The genes involved in the 27 export of the holdfast polysaccharide and anchoring of the holdfast to the cell were 28 previously discovered. In this study, we identify a cluster...

BACKGROUND The aim of this study was to define the minimal effective dose of antide (Iturelix) to prevent premature luteinizing hormone (LH) surges in in vitro fertilization (IVF) patients. METHODS In a prospective, single centre study, 144 IVF/ICSI patients were stimulated with r-hFSH from cycle day 2 and from cycle day 6 onwards, cotreated with daily 2 mg/2 ml (n=30), 1 mg/ml (n=30), 0.5 mg...

BACKGROUND The aim of this study was to assess whether low serum testosterone levels in men with newly diagnosed prostate cancer have an association to the endocrine status, prostate-specific antigen (PSA) levels, Gleason score, and androgen receptor expression. METHODS Besides a full clinical work-up, the following hormones were quantified in men with newly diagnosed prostate cancer by serum...

Abstract Study question Is ovarian stimulation (OS) with r-hFSH:r-hLH more effective than OS r-hFSH alone in women aged 35-42 normal reserve treated ART? Summary answer Compared to alone, for ART treatment was associated a significant increase clinical pregnancy and live birth per initiated cycle. What is known already Meta-analyses secondary analyses of data provide evidence that during improv...

BACKGROUND This Phase IV, open-label, multicentre, randomized study (MEnTOR) compared two low-dose recombinant human follicle-stimulating hormone (r-hFSH) protocols for ovulation induction. METHODS This study was conducted in six Middle Eastern countries between March 2009 and March 2011. Eligible women (18-37 years), with World Health Organization Group II anovulatory infertility, were rando...

Caulobacter crescentus cells adhere to surfaces by using an extremely strong polar adhesin called the holdfast. The polysaccharide component of the holdfast is comprised in part of oligomers of N-acetylglucosamine. The genes involved in the export of the holdfast polysaccharide and the anchoring of the holdfast to the cell were previously discovered. In this study, we identified a cluster of po...

Ovulation Induction and Oocyte Recovery Ovarian hyperstimulation was achieved using GnRH analogue (nafarelin acetate, Synarel®, Pfizer) along with human recombinant FSH (r-hFSH: Gonal-F®, MerckSerono) in a long down-regulation protocol. Starting gonadotrophin dose varied from 150-300 IU and was based on female age, body mass index, ovarian volume, basal FSH levels and the number of preantral fo...