نتایج جستجو برای: hexahydroquinoline
تعداد نتایج: 68 فیلتر نتایج به سال:
COX-2 inhibitory activities of some 1,4-dihydropyridine and 5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives were modeled by quantitative structure–activity relationship (QSAR) using stepwise-multiple linear regression (SW-MLR) method. The built model was robust and predictive with correlation coefficient (R2) of 0.972 and 0.531 for training and test groups, respectively. The quality of the mod...
The quinoline core structure is an important heterocyclic feature that can be found in numerous biologically active componds which exhibit a vast range of pharmacological properties such as antimalarial [1], antibacterial [2], antimicrobial [3], and antistaphylococcal activities [4]. Meanwhile, an important class of antibiotics possesses a 4-quinolone framework in their structure [5], and also ...
An aqueous solution of boric acid, as an efficient and green catalytic system, was efficiently utilized four-component cascade reaction of aryl aldehydes, dimedone, β-ketoesters and ammonium acetate to give hexahydroquinolines. By the reaction of boric acid with water, H+ was generated and efficiently catalyzed the reaction under mild and green condition. Also, optimization of the reaction cond...
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