Grass pea (Lathyrus sativus L.) is a diploid crop having 2n = 14 chromosomes. Four different plant types, heterozygous for reciprocal translocation (RT), RT-1, RT-2, RT-3, and RT-4 showing pollen semisterility, were isolated in induced mutant population of three varieties of grass pea. Transmission rate of these 4 translocations was studied in advanced selfed and intercrossed progenies, whereas...

cytes as a readily available source of this enzyme, its activity has been compared in 48 control subjects, seven homozygotes affected with homocystinuria, and 17 obligate heterozygotes. PHA-induced enzyme levels were highest in controls (mean ±SEM, 666.9±170.2 pmol cystathionine formed/mg protein per 4 h), intermediate in heterozygotes (114.4±27.3), and absent to severely deficient in homozygot...

Because there are no characteristic clinical or biochemical manifestations, the heterozygote state for lipoprotein lipase (LPL) deficiency has been difficult to detect. Measurements of postheparin plasma LPL activity and of LPL mass were performed in six families of probands with LPL deficiency to characterize the heterozygote state. LPL mass was measured in a sandwich enzyme-linked immunosorbe...

down’s syndrome, or 21 trisomy, is the most common autosomal abnormality, with incidence of 1 per 815 live births in iran. worldwide reports indicate that about 95% are regular trisomy, or nondisjunction, 1% are mosaic and 4% due to translocation. however, these values show a geographical variation. a cytogenetic study of down's syndrome, or trismoy 21, was carried out on 366 cases (202 males a...

This review summarizes results of field trials for the genetic control of Aedes aegypti conducted in coastal Kenyan villages in 1974-75. Two separate releases, in dry and wet seasons, of translocation-heterozygote males induced 60-70% sterility in offspring of native Ae. aegypti but did not reduce adult-mosquito population sizes in the release villages because of density-dependent larval mortal...

The chicken major histocompatibility complex (MHC) has strong genetic associations with resistance and susceptibility to certain infectious pathogens. The cell surface expression level of MHC class I molecules varies as much as 10-fold between chicken haplotypes and is inversely correlated with diversity of peptide repertoire and with resistance to Marek's disease caused by an oncogenic herpesv...

BACKGROUND Robertsonian translocations are structural chromosomal abnormalities caused by fusion of two acrocentric chromosomes. In carriers of such translocations, different modes of segregations would result in the formation of either balanced (alternate segregation mode) or unbalanced (adjacent 1, adjacent 2, and 3:1 segregation modes) gametes. In addition, there is an increased risk for imp...