k-Hierarchical probabilistic automata (k-HPA) are probabilistic automata whose states are stratified into k + 1 levels such that from any state, on any input symbol, at most one successor belongs to the same level, while the remaining belong to higher levels. Our main result shows that the emptiness and universality problems are decidable for k-HPAs with isolated cut-points; recall that a cut-p...

Human platelet alloantigens (HPAs) reside on functionally important platelet membrane glycoproteins and are caused by single nucleotide polymorphisms in the genes that encode them. Antibodies that form against HPAs are responsible for several clinically important alloimmune bleeding disorders, including fetal and neonatal alloimmune thrombocytopenia and posttransfusion purpura. The HPA-1a/HPA-1...

OBJECTIVE Amylin interacts with leptin to alter metabolism. We evaluated, for the first time, amylin- and/or leptin-activated signaling pathways in human peripheral tissues (hPTs). RESEARCH DESIGN AND METHODS Leptin and amylin signaling studies were performed in vitro in human primary adipocytes (hPAs) and human peripheral blood mononuclear cells (hPBMCs) and ex vivo in human adipose tissue (...

Synthesis of 3,1,5-benzoxadiazepines from the condensation of o-phenylenediamine (o-PDA) and acyl chlorides in the presence of a catalytic amount of various heteropolyacids (HPAs) is reported.

Petechiae or echymoses and severe thrombocytopenia (< 20 × 10 platelets/litre) is a worrying and serious condition in newborn infants. Rapid correction of the platelet count is essential to prevent cerebral bleeding and associated life long disability, and this should be combined with laboratory investigations to confirm the clinical diagnosis. Prospective studies have revealed that the most li...

Alloimmunization to human platelet antigens (HPAs) may occur either during pregnancy, when a HPA‑negative mother gives birth to a newborn who inherits HPAs from the father, or following blood transfusion or stem cell transplantation. Antiplatelet alloantibodies do not cause thrombocytopenia in a patient, but their detection must always be recorded in medical records because they may induce feta...

New mixed H4[SiMonWn-12O40] (n = 6 and 9) Keggin type heteropolyacids (HPAs) have been successfully synthesized, as confirmed by single-crystal XRD, Raman IR spectroscopy analysis. The resulting polyoxometallates were used for preparation of hydrotreatment catalysts. Mo(W)/Al2O3 catalysts synthesized incipient wetness impregnation alumina support with water solutions prepared HPAs corresponding...