نتایج جستجو برای: heterocycle

تعداد نتایج: 914  

2014
Pravin Patil Kareem Khoury Eberhardt Herdtweck Alexander Dömling

Novel scaffolds are of uttermost importance for the discovery of functional material. Three different heterocyclic scaffolds easily accessible from isocyanoacetaldehyde dimethylacetal 1 by multicomponent reaction (MCR) are described. They can be efficiently synthesized by a Ugi tetrazole multicomponent reaction of 1. We discuss the synthesis, 3D structures, and other physicochemical properties.

Journal: :Chemical communications 2012
Virtudes Pardo-Rodríguez Elena Buñuel Daniel Collado-Sanz Diego J Cárdenas

Reaction of a variety of 1,7-enynes with bis(pinacolato) diboron catalysed by Pd bis(trifluoroacetate) affords homoallylic and allylic boronates containing a six membered carbo- or heterocycle, by formation of C-C and C-B bonds.

2008
Feng-Xia Zhu Jian-Feng Zhou Gui-Xia Gong

In the mol-ecule of the title compound, C(9)H(7)NOS(2), the heterocycle and the phenyl ring are oriented at a dihedral angle of 72.3 (1)°. Adjacent mol-ecules are connected through C-H⋯O inter-actions.

Journal: :Organic & biomolecular chemistry 2016
A Hemi Cumming Sarah L Brown Xu Tao Claire Cuyamendous Jessica J Field John H Miller Joanne E Harvey Paul H Teesdale-Spittle

Pateamine A is a naturally occurring metabolite extracted from the marine sponge Mycale hentscheli. It exhibits potent cytotoxicity towards cancer cell lines and has been shown to target protein translation initiation via inhibition of the function of eukaryotic initiation factor 4A proteins. We have synthesised a simplified analogue of pateamine A, consisting of the skeletal core of the natura...

2011
Matthew P. Akerman Ross S. Robinson Cathryn A. Slabber

The title compound, C(16)H(12)BClN(2), is one in a series of diaza-borinanes, derived from 1,8-diaminona-phthalene, featuring substitution at the 1, 2 and 3 positions in the nitro-gen-boron heterocycle. The structure deviates from planarity, the torsion angle subtended by the p-chloro-phenyl ring relative to the nitro-gen-boron heterocycle being -44-.3(3)°. The mol-ecules form infinite chains w...

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