نتایج جستجو برای: hes 130
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مقدمه: کلوییدها در مایع درمانی بیماران نقش بسزایی دارند، ولی این محلول ها اثرات سویی بر روی سیستم انعقادی می گذارند که باعث محدودیت در استفاده از آن ها می شود. به تازگی انواع جدیدی از این محلول ها در دسترس قرار گرفته اند که اثرات سوء انعقادی کمتری برای آن ها ذکر شده است. هدف از این مطالعه، بررسی اثرات انعقادی انواع جدید در مقایسه با انواع قدیمی بود. روش ها: در یک کارآزمایی بالینی دوسوکور 58 بیم...
BACKGROUND The effects of hydroxyethylstarch (HES) 130/0.4 6% and gelatin 4% on inflammation, endothelial integrity, and renal function after cardiac surgery were compared. METHODS Sixty patients aged >80 yr undergoing cardiac surgery were randomized to receive gelatin (n=30) or HES 130/0.4 (n=30). The colloid was used in the priming of the cardiopulmonary bypass circuit (500 ml) and for volu...
BACKGROUND This study compared the effects of a potato-based hydroxyethyl starch (HES) with those of a maize-derived HES preparation on coagulation in cardiac surgery patients. METHODS Sixty patients undergoing elective cardiac surgery with cardiopulmonary bypass were allocated randomly to receive either a potato-derived HES (6% HES 130/0.42) (n=30) or a waxy-maize-derived HES (6% HES 130/0.4...
INTRODUCTION Third-generation hydroxyethyl starch (HES) is now approved also for the use in children, but safety studies including large numbers of pediatric patients are still missing. Therefore, we performed an European multicentric prospective observational postauthorization safety study (PASS) to evaluate the use of HES 130/0.42/6:1 in normal saline (ns-HES) or a balanced electrolyte soluti...
BACKGROUND AND OBJECTIVES Hydroxyethyl starch (HES) 130/0.4 is considered an effective plasma expander when compared to crystalloids. There is controversy around its superiority regarding hemodynamic optimization and about possible detrimental effects on coagulation. The aim of this study was to compare the effects of HES 130/0.4 to lactated Ringer solution during hip arthroplasty in adult pati...
CITATION Perner A, Haase N, Guttormsen AB, Tenhunen J, Klemenzson G, Åneman A, Madsen KR, Møller MH, Elkjær JM, Poulsen LM, Bendtsen A, Winding R, Steensen M, Berezowicz P, Søe-Jensen P, Bestle M, Strand K, Wiis J, White JO, Thornberg KJ, Quist L, Nielsen J, Andersen LH, Holst LB, Thormar K, Kjældgaard AL, Fabritius ML, Mondrup F, Pott FC, Møller TP, Winkel P, Wetterslev J; 6S Trial Group; Scan...
BACKGROUND Hydroxyethyl starch (HES) [corrected] is widely used for fluid resuscitation in intensive care units (ICUs), but its safety and efficacy have not been established in patients with severe sepsis. METHODS In this multicenter, parallel-group, blinded trial, we randomly assigned patients with severe sepsis to fluid resuscitation in the ICU with either 6% HES 130/0.42 (Tetraspan) or Rin...
1249 December 2013 D URING the past year, there has been substantial discussion about hydroxyethyl starches (HESs), with some claiming that neither efficacy nor safety has been demonstrated. In this issue of ANEStHESIoloGy, Van der linden et al.1 report a clinical efficacy trial with HES 130/0.4 that has several interesting issues. Some, but not all, are discussed relatively briefly, as space l...
Comparison of HES 130/0.42 and HES 200/0.5 for hemodynamic stabilisation in major urological surgery
Purpose: Different hydroxyethyl starches (HES) may lead to different volume effects. We compared a new HES130/0.42 with an established HES200/0.5 with respect to perioperative volume requirements, hemodynamic effects, safety and tolerability. Methods: After approval of the local ethics committee we investigated in a prospective, randomized double-blinded clinical trial 100 adult patients schedu...
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