The present study evaluated the potential benefit of supplementation with Heracleumpersicum as an adjunctive therapy to atorvastatin in dyslipidemic subjects. In a randomized, open-label, clinical trial, 100 dyslipidemic subjects were randomly assigned to: (1) H. persicum group (n=50, completers=18), receiving H. persicum extract (500 mg/day) + atorvastatin (10 mg/day) for 8 weeks, or (2) atorv...

Bunium persicum (Boiss.) is an economically important medicinal plant growing wildly in arid regions in Iran. The fruit of B. persicum is widely used in traditional Iranian medicine to control colic pain and dysmenorrhoea. The aim of the current study was to determine antinociceptive mechanisms of B. persicum essential oil using an acetic acid-induced writhing test as a model of visceral pain a...

Background and objectives: Heracleum persicum (Golpar)is a native medicinal plant of Iran which belongs to Apiaceae family. The fruits of the plant have been used as spice for flavoring. They have also showed carminative, antioxidant, anticonvulsant, analgesic, anti-inflammatory, immunomodulatory and cytotoxic properties. In this study, toxicity of different fractions ...

In order to investigate the medicinal species from montain of ShirKooh (Up village), in Yazd provience, Iran on three species by scientific names were Heracleum persicum Desf. ex Fisch., C.A.Mey. & Avé-Lall.; Ziziphora clinopodioides Lam. and Nepeta asterotricha Rech.f. were collected on June, July and August 2011. Then all samples essential oils were extracted by hydro-distillation method (cla...

Background and objectives: Heracleum persicum aerial parts have been used in Iranian folk medicine for their therapeutic activities and as a spice and flavoring agent in Iranian foods and pickles. The present research was conducted to evaluate the pharmacognostic profile of H. persicum which will be useful in standardization for quality, purity, and sample ide...

Studies have demonstrated that plant extracts possess various biological characteristics, including immunomodulatory activity. Heracleum persicum Desf. (Apiaceae), a medicinal plant native to Iran, was studied for its immunomodulatory activity. Immunomodulatory activity of different doses of an aqueous extract of H. persicum, was evaluated in female Swiss albino mice. Mice were treated with thr...

Background: Leishmaniasis is a parasitic disease that occurs in subtropical and tropical regions with approximately 350 million people worldwide 2 new cases annually. The annual increase cutaneous leishmaniasis (CL) observed, especially endemic areas such as Iran. Since there no effective vaccine, the detection of natural anti-leishmanial products essential. Objective: purpose this study was to...