Using enantioselective M D G C the enantiom eric d istribution o f alkan-(alken-)2-yl-acetates from bananas is achieved. A fter simple acetylation their corresponding alcohols 2-pentanol, 2-hexanol, 2-heptanol and (Z)-4-hepten-2-ol respectively are also exactly stereodifferentiated by the same method. All com pounds investigated esters as well as alcohols exhibit a rem arkable excess o f the (5...

Volatiles are important quality components in tea (Camellia sinensis) flowers. Albino plants mutant with diverse abnormal metabolisms. However, whether the metabolisms of volatiles flowers from albino cultivars remains unclear. In this study, headspace solid-phase microextraction coupled to gas chromatography-mass spectrometry and aroma evaluation were conducted investigate volatile composition...

The enzymatic hydrolysis of meso-1,7-diacetoxy-2,6-dimethylheptane 5, prepared from 2,6-dimethylhepta-1,6-diene 6, gave the (2S,6R)-7-acetoxy-2,6-dimethyl-1-heptanol 1, which was transformed to the (2R,6R)-2,6,10-trimethyl-1-undecanol 7. In this manner, the C14 side chain of a-Tocopherol was synthesized from 2,6-dimethylhepta-1,6-diene 6 in only 5 steps.

Transport across gap junction channels (GJCs) between neighboring cells is critical to synchronizing cell's electrical and metabolic activities and maintaining cell homeostasis. Here we present a non-invasive microfluidic method to measure molecular diffusion across GJCs in multiple 1D cell arrays in real time. Using the chip, selective loading of a membrane permeant fluorescence dye (carboxyfl...

The activity of gap junction channels between pairs of neonatal rat heart cells in culture was studied under control conditions and during uncoupling procedures by using dual whole-cell voltage clamp techniques. Under control conditions gap junctional conductance ranged from 0.05 to 35 nS. In cell pairs exhibiting low gap junctional conductance (less than 500 pS), single-channel events with a u...

Incubation of hippocampal slices in zero-Ca(2+) medium blocks synaptic transmission and results in spontaneous burst discharges. This seizure-like activity is characterized by negative shifts (bursts) in the extracellular field potential and a K(+) wave that propagates across the hippocampus. To isolate factors related to seizure initiation, propagation, and termination, a number of pharmacolog...