Patients with Beckwith-Wiedemann syndrome (BWS) are known to be at an increased risk for childhood malignancies, particularly Wilms tumor and hepatoblastoma. We report a case of genetically confirmed BWS in a 5-month-old girl who presented with a 9.5-cm abdominal mass associated with elevated α-fetoprotein levels. The clinical impression was strongly suggestive of hepatoblastoma. Histologic exa...

AbstractPurpose Hepatoblastoma is the most common liver malignancy in children. In order to advance therapy against hepatoblastoma, novel immunologic targets and biomarkers are needed. Our purpose this investigation examine hepatoblastoma transcriptomes for expression of a class genomic elements known as Human Endogenous Retrovirus (HERVs). HERVs abundant human genome biologic...

Hepatoblastoma is thought to originate from embryonal hepatic tissue, and most of these tumors occur in children under the age of 2 years. Hepatoblastoma in adults is extremely rare, and the prognosis is much worse than the mixed hepatoblastoma of childhood. We experienced a case of mixed hepatoblastoma in a 51 year old female patient. She had been suffering from a mild pain and a palpable lump...

Hepatoblastoma (HB) is a rare malignant tumour of the liver and usually occurs in the first three years of life. Most of these tumours arise in the embryo; hence it seems to be unusual that hepatoblastoma occurs in adults and is an exceptional cause of primary malignant liver tumour in adult patients. The diagnosis is often overlooked, and patients might be diagnosed at late stages of the disea...

hepatoblastoma (hb) is a rare tumor of infancy and childhood manifesting with hepatomegaly and abdominal distention. it is seen with increased frequency in association with congenital hemihypertrophy and renal anomalies. metastases to other organs, including the lungs, lymph nodes and even ovaries is well known. but cerebral metastasis of this tumor, especially in the absence of metastasis to o...

conclusions the clinical features are effective indicators for distinguishing ihh from hbl, and the spectral doppler may be a useful adjunct parameter for differential diagnosis. objectives to study the clinical manifestations and the ultrasound features of the pediatric patients for distinguishing ihh from hbl. patients and methods between 2002 and 2012, thirteen children with ihh and 38 child...

UNLABELLED This study is to review and retrieve data on adult hepatoblastoma (HB) from English literatures in order to gain a better understanding of this disease. We performed Medline, PubMed (from January 1966 to February 2008), and library searches (National Science and Technology Library, Beijing, China, and Wenzhou Medical College Library, from January 1980 to February 2008) using the key ...

AIMS To review all the case reports or case series of patients with adult hepatoblastoma. METHODS A search of all case reports on adult hepatoblastoma in the English literature was performed using the PubMed database. Demographic information, clinical findings, treatment modalities and outcomes were extracted and analyzed. RESULTS A total of 36 English articles and 40 patients with adult he...

Hepatoblastoma is the most common type of malignant liver tumor in children and occurs most frequently in patients two years of age and younger. The outcomes for children with hepatoblastoma have been improving in recent years due to the introduction of cisplatin-based chemotherapy regimens. Recently, performing liver transplantation after neoadjuvant chemotherapy has become increasingly advoca...