Toll-like receptor 4 (TLR4), a proximal signalling receptor in innate immune responses to lipopolysaccharide of gram-negative pathogens, is expressed in the heart. Accumulating evidence have consolidated the notion that TLR4 plays an essential role in the pathogenesis of cardiac dysfunction. However, the molecular mechanisms of TLR4 responsible for ischemia-induced cardiac dysfunction remain un...

Conservation of energy usage is essential in chemical process plants due to the expanded users and demands alongside carry-on hike prices. This study analyzed performance savings a heat exchanger network (HEN). It based on decreasing utility while increasing process-to-process exchange HEN using path combination approach at different recovery temperatures (HRATs). The generates combined options...

The optimization of heat exchanger network (HEN) synthesis still remains an open problem because of the complexity of the space comprising all the possible solutions, and most of the proposed methods introduce simplifying assumptions that mainly affect the topological features of the candidate solutions considered and thus artificially limit the boundaries of the search space. This work is devo...

Here we report a fourteen-month-old fourlegged local hen in Nigeria with two cloacae and three caeca. The hen walked with only the normal two limbs, which were larger and cranial to the extra two limbs. The extra limbs were usually suspended in the air and pointed caudally during motion, being attached to the pygostyle by cartilage and skin tissue. Investigations of the bird were carried out us...

A semiempirical shell-correction method including ellipsoidal deformations is used to determine binding energies of open-shell, unpolarized HeN clusters. Shell effects, shapes, and other ground-state properties ~like the chemical potential! are determined. HeN clusters are found to be substantially less deformed due to their relatively high surface energy as compared to that of alkali-metal clu...

Susceptibilities of 5 different mice strains, including C3H/HeN, BALB/c, C57BL6, FvB and ICR, to Echinostoma hortense infection, was evaluated. The worm expulsion rate, worm size and egg production were observed from 1 to 8 weeks after infection with 30 metacercariae. C3H/HeN and ICR mice showed the highest worm maturation rates. The worm recovery rate and the number of eggs per gram (EPG) of f...