One of the underlying challenges in any surgical procedure is to maintain or regain hemostasis. Classic surgical training reinforces the axiom that careful attention to surgical hemostasis can help reduce blood loss and transfusion and ultimately improve patient outcomes. There are many challenges to hemostasis in the vascular surgery population due to advanced age at presentation, prior proced...

Hemostasis is a delicate, dynamic and intricate system, in which pro- and anti-coagulant forces cooperate for either maintaining blood fluidity under normal conditions, or else will prompt blood clot generation to limit the bleeding when the integrity of blood vessels is jeopardized. Excessive prevalence of anticoagulant forces leads to hemorrhage, whereas excessive activation of procoagulant f...

Here we review the zebrafish hemostatic system, its relevance to mammalian hemostasis, and its efficacy as a vertebrate genetic model to further the understanding of hemostasis and thrombosis.

Background and objective: Traumatic epistaxis is a complicated and sometimes life-threatening complication of skull-base fractures. The aim of the study was to observe the effect of a new hemostatic device on treatment of intractable traumatic epistaxis induced by craniofacial basicranial fractures. Methods: The study included 85 patients with intractable traumatic epistaxis induced by craniofa...

BACKGROUND The most suitable mechanical endoscopic hemostasis for a bleeding Dieulafoy's lesion (DL) is not yet well established. OBJECTIVE To compare the hemostatic efficacy and clinical outcome of endoscopic hemoclip placement (EHP) and endoscopic band ligation (EBL). DESIGN Retrospective, single-center study. SETTING A tertiary-care referral university hospital. PATIENTS Sixty-six pa...

BACKGROUND Most of the presently used percutaneous arterial closure devices (PACD) for hemostasis after interventional vascular procedures are effective, but carry risk of complications by deposition of a foreign body. A new promising externally applied PACD - chitosan-based HemCon Bandage (HCB) was explored in sheep. The HCB hemostatic efficacy and complications occurring with its use were com...

The process of fibrin clot formation is a series of complex and well-regulated reactions involving blood vessels, platelets, procoagulant plasma proteins, natural inhibitors, and fibrinolytic enzymes. Vasculitis can be caused by a variety of different agents as bacteria, viruses, protozoal, rickettsial organisms, toxic, drugs, medications, and neoplasms. The most common cause of vasculitis is t...