Background: Diltiazem is a calcium channel blocker that can prevent absorption by myocytes and decrease the tone of internal anal sphincter. Thus, it be used for treatment fissures; however, its effect on post-hemorrhoidectomy pain unclear. Accordingly, current study aimed to evaluate topical diltiazem pain. Methods: This cohort included 50 candidates hemorrhoidectomy referred Shahid Mohammadi ...

BACKGROUND Methylene blue (MB) has been found to have unique analgesic property through temporary disruption of sensory nerve conduction. In anorectal surgery, MB is widely used as a biologic stain but the analgesic effect has never been studied. Thus, a literature review completed with critical appraisal is required to find out its efficacy. METHODS A review has been run to find out its effi...