The anode Is at the left, the origin at the rlt. Above Is a control consIstIng of HbA, F. S. and A2.Below Is the concentrated column eluate. Note the fast hemoglobIn band at the far left and carbonIc anhy-&ase B near the origIn atthe rIght In the pattern for the column eluate 1250 CLINICAL CHEMISTRY. dure is applicable also to other situations , e.g.,to the measurements of specific radioactivit...

1. Imamura T, Fujita S, Ohta Y, Hanada M, Yanase T. Hemoglobin Yoshizuka (G10(108) β asparagine → aspartic acid): a new variant with a reduced oxygen affinity from a Japanese family. J Clin Invest 1969; 48:2341–8. 2. Moo-Penn WF, Wolff JA, Simon G, Vacek M, Jue DL, Johnson MH. Hemoglobin Presbyterian: β108 (G10) asparagine leads to lysine, a hemoglobin variant with low oxygen affinity. FEBS Let...

abstract background iron-deficiency anemia is a widespread public health problem with major consequences for human health especially, children. however, in a fraction of patients an underlying cause is never found during routine investigation. recent studies have suggested an association between helicobacter pylori (h. pylori) infection and iron-deficiency anemia. case presentation here is repo...

We demonstrate kinetically that the reaction of 5,5V-dithiobis(2-nitrobenzoate) with the CysF9[93]h sulfhydryl group of domestic cat hemoglobins is a reversible process. In the major hemoglobin, in which the NH3 + terminal group of GlyNA1[1]h is free, kf, the apparent forward second order rate constant, has a complex pH dependence profile. In the minor hemoglobin, the NH3 + terminal group of Se...

hemoglobinopathies are the most common single gene disorders worldwide with a considerable frequency in certain area particularly mediterranean and middle eastern countries. hemoglobinopathies include structural variants of hemoglobin (hb s, hb c, hbe,…) and thalassaemias which are inherited defects in the globin chains synthesis. the present study was conducted to determine the prevalence of h...