To cure a patient by removing his illness extracting blood is very old one. Now this process, bloodletting, placed on rational basis with therapeutic apheresis using hollow fiber membranes, being our clinical practice. Based many years of experience extracorporeal circulation in end-stage renal disease, the authors herein give an overview TA hematologic diseases, immunologic or non-immunologic ...

Splenectomy, while often necessary in otherwise healthy patients after major trauma, finds its primary indication for patients with underlying malignant or nonmalignant hematologic diseases. Indications of splenectomy for hematologic diseases have been reducing in the last few years, due to improved diagnostic and therapeutic tools. In high-income countries, there is a clear decrease over calen...

• Microbiota includes commensal and pathogenic microorganisms colonizing human body. Dysbiosis may favour the development of oncologic benign hematologic diseases. Chemotherapy immunesuppression worsen dysbiosis infections. Antibiotic prophylaxis/therapy be detrimental for microbiome composition. Novel target therapies induce possibly impacting on outcome. Growing evidence suggests impact alter...

ultrasonography is a useful procedure in evaluation of spleen size in different clinical conditions. in this study, we used it to evaluate spleen size in patients with various heptologic, hematologic and autoimmune diseases. to express spleen size, a spleen index (si), the product of the transverse diameter and its perpendiculr diameter measured on the maximum-sectional image of the spleen, was...