background self-inflicted burn injuries carry considerable mortality and morbidity among otherwise fit young individuals. this study assessed the epidemiologic pattern and outcome of these injuries in a burn care facility in pakistan. methods the study was carried out at pakistan institute of medical sciences (pims) burn care centre in islamabad over a period of 2 years. it included all adult p...

Previous studies demonstrate that thermal injury decreases circulating levels of insulin growth factor I (IGF-I) and alters the plasma concentration of several IGF binding proteins (IGFBP), but the mechanisms for these alterations have not been elucidated. In the current study, a 30% total body surface area full-thickness scald burn was produced in anesthetized rats, and animals were studied 24...

background: general practitioners are the first who visit burn patients and they first calculate burn size and required fluid for the patient. error in calculation can be disastrous. the purpose of this study is to compare four methods of estimating burn size to teach students. methods: this is a descriptive-analytic study on 37 medical students. four methods of estimating burn percentage was t...

BACKGROUND The systemic responses to burns (in particular, elevated levels of catecholamines and stress hormones) have been shown to have an impact on cardiac function for at least 3 years in children with burns. However, it is not clear if these changes lead to long-term effects on the heart. The aim of this study was to assess whether pediatric burn injury is associated with increased long-te...

To mimic ischemic heart disease in humans, several animal models have been created, mainly in rodents by surgically ligating their coronary arteries. In the present study, by simply inducing burn injuries on the bullfrog heart, we reproduced abnormal ST segment changes in the electrocardiogram (ECG), mimicking those observed in ischemic heart disease, such as acute myocardial infarction and ang...

羽野 寿 ・岩田 平太郎 ・岩田 宣芳 ・本間 弘茂 Since the well known hypothesis proposed by Burn and Rand (1) in 1958 that tyra mine exerts its sympathomimetic action through release of catecholamine (CA) from its storage sites, there have been many studies on this using various tissues in vitro and in vivo (2-6), and this hypothesis is now generally accepted. Kottegoda (7) found that nicotine first had a negative ...